advertisement
 

  Back to Ask the Diabetes Team Ask the Diabetes Team
Question:

From Arlington, Virginia, USA:

The July issue of Pediatrics contained an article that suggests that high doses of folate and/or vitamin B6 normalized endothelial (vascular) dysfunction in children with type 1 diabetes. This appears to be a major finding. What are your thoughts on this article and the use of these supplements at the doses described in the article or in the alternative of their recommended upper tolerable limits?

Answer:

The article used 5 mg of folate and 100 mg of B6, one or the other. That's a lot, at least 10 times the RDA (Recommended Daily Allowance). It was an eight week study. Your question is whether a child should take that much folate for the rest of his/her life...no one knows. Is it safe? I suppose we think so, but, as an example, when one of the big studies with vitamin E was finished, there was some question of increased risk in the treated group. So, I can't tell anyone to take that much folate.

Many dark green vegetables, plus a multivitamin, would get somewhere in the 600 to 800 mcg range or 20% of the treatment range. I know that would be safe. Remember that we need a little bit of the vitamins. When given in big doses, they become a medicine just like penicillin.

LD

DTQ-20060810224229
Original posting 29 Aug 2006
Posted to Other

  
advertisement


                 
  Home Return to Top

Last Updated: Tuesday April 06, 2010 15:10:08
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.

This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
By using this site, you agree to our Terms of Use, Legal Notice, and Privacy Policy.
© Children with Diabetes, Inc. 1995-2015. Comments and Feedback.