From Victorville, California, USA:
I have been told that type 1 diabetes is hereditary. I was diagnosed in 1966 at the age of seven. No one else in my family was ever diagnosed. So, if it is hereditary, why am I the only one is my genealogical history that has ever been diagnosed?
The inheritance pattern for type 1 diabetes is different than that of type 2 diabetes. For offspring of parents with type 2 diabetes, there is roughly a 50% chance of inheriting diabetes. For those with type 1 diabetes, it is much less, at around 10%. This means that many people develop type 1 diabetes without other recent members of their family having had the disease. We believe that type 1 diabetes has a complicated inheritance pattern where you inherit a predisposed risk for the disease, but also require some environmental hit, such as an infection or another exposure, to get the disease. It is also interesting that men with type 1 diabetes have a slightly higher risk of offspring developing type 1 diabetes, compared to women. The risk is something like 10 to 15% for men, but only 5 to 10% for women.
Original posting 2 Apr 2007
Posted to Genetics and Heredity
Last Updated: Tuesday April 06, 2010 15:10:12
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.