Pancreas/beta cells can either be overused or underused in type 2 diabetes. How can its overuse and under use impact or damage it?
I prefer to think of type 2 diabetes to be associated with insulin resistance (overactive insulin secretion) and inappropriately low insulin secretion (underactive insulin secretion). Most people believe that both components exist coincidentally at the time of diagnosis. It is not that overuse or underused damages beta cells. It is that the abnormalities are already there at diagnosis. Many people have insulin resistance but only a few people have diabetes. It is thought that most of the genetic abnormalities determined to date reflect on impaired insulin secretion. Therefore, it is as if those pre-determined to have diabetes in the face of insulin resistance are going to be those with the genetic defects to ramp up insulin secretion.
Last Updated: Tuesday April 06, 2010 15:10:18
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.