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Question: From Egypt: I'm a 27-year-old male doctor and I am overweight. For two weeks, I felt polyuria and polydipsia so I checked my random blood glucose. It was 600 mg/dl [33.3 mmol/L]. My fasting blood sugar was 244 mg/dl [13.6 mmol/L]. After ingesting 75 mg of glucose, my blood sugar was 456 mg/dl [25.3 mmol/L]. My glycosylated hemoglobin was 8.6. I sought medical advice and my doctor recommended Glucovance 500/5, diet, and exercise. I was having great control for about a week when, one day, I forgot to take my medication. Even without the medication, my blood sugars were in range. It's now been four days since I took the Glucovance and my postprandial blood sugars have been between 130 and 140 mg/dl [7.3 and 7.8 mmol/L]. My fasting blood sugars are 80 to 90 mg/dl [4.5 to 5.0 mmol/L]. I'm so confused about that and I don't know if I have type 2 diabetes or not. I plan to keep on dieting and exercising to reduce my weight, but can you help clarify my diagnosis? Answer: From what you have told me, you clearly have type 2 diabetes. It is not a surprise that your blood sugars might remain normal for a while, even though you have stopped your medication. After successful treatment of high blood sugars, no matter how they are decreased (insulin, pills, diet, etc.), the insulin-producing cells in the pancreas recover from the high glucose conditions. What I think you will find, if you remain off the medication, is that your blood sugars will gradually rise again. You might want to talk your physician about using metformin as a single drug. I think the recommendations by the European Association for the Study of Diabetes and the American Diabetes Association recommend this as a first-line drug. There is net weight loss with the medication and no hypoglycemia. With Glucovance, there is a mixture of metformin and glyburide (a sulfonylurea). The glyburide is associated with weight gain and hypoglycemia. JTL DTQ-20090720073658 Original posting 27 Jul 2009 Posted to Diagnosis and Symptoms and Type 2

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			Jump to a new section --[ Getting Around ]-- Home Page What's New Privacy Policy Search --[ People ]-- Family Support Network Adults with Diabetes Care Photos Chat Rooms Conferences Kids with Diabetes Parents Parent Humor Scholarships and Financial Aid Grandparents Humorous Tidbits Jobs Mailing Lists CWD Forums Poetry and Art Videos Polls Quilt for Life Surveys Blogs --[ Clinic ]-- Ask the Diabetes Team Alternate Site Testing Alternative Treatments Care Suggestions CWD Español Diabetes Basics Diabetes at School 504 Plans Diabetes Camps Diabetes Dictionary Insulin Pumps Nutrition Podcasts Presentations Products Product Marketplace Sports Studies Warning Signs --[ Sources ]-- News and Information Diabetes Advocacy Links to Other Web Sites Press Releases Regional Information Services Support Groups --[ Feedback ]-- About CWD Advertise Awards Contribute Your Experiences Disclaimer Letters to the Editor Logos and Linking Share our Brochures

Last Updated: Tuesday April 06, 2010 15:10:17
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