Is it possible that extra insulin can interfere in filtration from micro-vessels and from liver, kidney, etc. and cause some problem in view of that it is a big molecule and exogenous insulin can be bit odd for body's normal handling? Excess and continual exposure of insulin may also cause its decreased use due to insulin resistance and decreased degradation so circulating insulin can be more.
The rate limiting step in insulin absorption is absorption from a subcutaneous site. It is rather efficiently absorbed without much difficulty. Previous studies have shown that insulin resistance is not related to absorption at the injection site.
Original posting 31 Mar 2010
Posted to Insulin
Last Updated: Tuesday April 06, 2010 15:10:18
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