At the age of 53, I am 5 feet, 7 inches tall. My blood sugars are between 200 and 250 mg/dl [11.1 and 13.9 mmol/L]. Controlling my diet did not work, nor did metformin. For eight years, I have been taking acarabose and voglibose but they have been upsetting my stomach. So, I now need to take a sulfonylurea. I have VPC (ventricular premature contraction). Which is better for me, glimepiride (1 mg) or gliclazide (30 mg film coated) or dpp-4 (dipeptidyl peptidase 4)?
Sulfonylureas are not necessarily a first-line drug. However, they do have their place in the treatment of type 2 diabetes. They are inexpensive and do work. Of the ones you noted, I prefer glimepiride over gliclazide. There is a theoretical benefit to the glimepiride having less cross-reactivity with the heart. The dpp-4 inhibitors are very expensive and not very potent. Although this might be helpful to some, if your HbA1c is 1% over target, the dpp-4 might not be potent enough to bring down to target.
Last Updated: Tuesday June 04, 2013 16:12:36
This Internet site provides information of a general nature and is designed for educational purposes only. If you have any concerns about your own health or the health of your child, you should always consult with a physician or other health care professional.
This site is published by T-1 Today, Inc. (d/b/a Children with Diabetes), a 501c3 not-for-profit organization, which is responsible for its contents. Our mission is to provide education and support to families living with type 1 diabetes.
© Children with Diabetes, Inc. 1995-2016. Comments and Feedback.