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Research News From 1998

  1. Inhaling instead of injecting insulin reports on a small study performed at the Johns Hopkins University School of Medicine in Baltimore, Maryland. (24 December 1998)
  2. Aradigm Initiates Phase II Testing of Inhaled Insulin in the United States. (24 December 1998)
  3. First-Ever "Islets Alone" Transplant Performed On Type 1 Diabetes Patient reports on Jackie Warren Demijohn, who received an islet and bone marrow transplant at the Diabetes Research Institute. (13 December 1998)
  4. ACE inhibitors are prescribed to help reduce the risk of developing kidney disease in people with diabetes who have microalbuminuria. (Free Medscape membership required.) (13 December 1998)
  5. Stem Cell Research Offers Potential Benefits for Persons with Diabetes, reports the JDF. (6 December 1998)
  6. Diabetes is linked to embryonic cell death in pregnant women with poor blood sugar control, according to a recent laboratory research study done in mouse embryos. This article reconfirms the well-known advice that women with diabetes who are planning a pregnancy should get their blood sugar levels under control prior to conception. (6 December 1998)
  7. Why Are Kids Getting Type 2?, from the December 1998 issue of Diabetes Forecast, highlights the growing problem of kids being diagnosed with Type 2 diabetes. (6 December 1998)
  8. In "Previous Episodes of Hypoglycemic Coma Are Not Associated With Permanent Cognitive Brain Dysfunction in IDDM Patients on Intentive Insulin Treatment," researchers studying 108 patients with adults onset Type 1 diabetes concluded that hypoglycemic coma was not associated with long-term impairment of brain function. (Diabetes 47:1909-1914, 1998) (29 November 1998)
  9. An article about Bloodless Testing appeared in the October 1998 issue of Scientific American. (22 November 1998)
  10. Warner-Lambert to Begin Diabetes Prevention Study with Rezulin. (22 November 1998)
  11. Cloning and Sequencing of the Pancreatic Islet Neogenesis Associated Protein (INGAP) Gene and Its Expression in Islet Neogenesis in Hamsters reports on interesting research aimed at regenerating islet cells. (22 November 1998) First "Islets Alone" Transplant Performed On Type 1 Diabetic Patient at the Diabetes Research Institute. (15 November 1998)
  12. Diabetes Research Meeting Reveals Progress toward Disease Cure in Three Major Areas reports on data presented at the first International Progress Report on Diabetes Research. (15 November 1998)
  13. New Insights Into the Clinical Benefits of Insulin Lispro reports that lower HbA1c levels reported with the use of Lispro are associated with a 20% reduction in the risk of developing retinopathy. Membership in Medscape required. (8 November 1998)
  14. Vaccination Against Type 1 Diabetes Mellitus by Early Immunotherapy with Autoantigens reports on work done with NOD mice that prevents Type 1 diabetes through early vaccination with recombinant GAD65 and GAD67 proteins. Membership in Medscape required. (8 November 1998)
  15. New Approaches to Preventing and Treating Type 1 Diabetes: Discovering a Method to Preserve Beta Cell Mass after Diagnosis Should Remain a Key Research Focus summarizes the current state of prevention research and suggests that research designed to minimize loss of islet function after diagnosis is largely being ignored. Membership in Medscape required. (8 November 1998)
  16. Attempts to Control the Glycemic Response to Carbohydrate in Diabetes Mellitus: Overview and Practical Implications discusses various dietary attempts to manage blood sugar levels, including the glycemic index. Membership in Medscape required. (8 November 1998)
  17. Children who have, or may have, Type 2 diabetes may qualify to participate in a research study of an investigational treatment for Type 2 diabetes. (25 October 1998)
  18. The Journal of the American Medical Association offered a perspective on Development of Noninvasive Methods to Monitor Blood Glucose Levels in People With Diabetes in July 1998. (25 October 1998)
  19. Management of Infants of Diabetic Mothers provides an abstract of a study that concludes that "With modern management, fewer morbidities can be expected in infants of diabetic mothers." (25 October 1998)
  20. The American Diabetes Association has Questions and Answers about the United Kingdom Prospective Diabetes Study (UKPDS) which confirmed the benefits of tight control for people for Type 2 diabetes. (11 October 1998)
  21. Effect of Continuous Subcutaneous Insulin Infusion With Lispro on Hepatic Responsiveness to Glucagon in Type 1 Diabetes concludes that use of lispro in pumps leads to increased sensitivity of the liver to glucagon and therefore could potentially reduce the risk of severe hypoglycemia. (Diabetes Care 21:1627-1631, 1998) (4 October 1998)
  22. Meta-Analysis of the Effect of Insulin Lispro on Severe Hypoglycemia in Patients with Type 1 Diabetes concludes that use of lispro insulin instead of Regular insulin in patients who are intensively treated reduces the risk of severe hypoglycemia (defined as coma or requirement for glucagon or IV glucose). (Diabetes Care 21:1726-1731, 1998) (4 October 1998)
  23. Effect of Bacille Calmette-Guérin Vaccination on C-Peptide Secretion in Children Newly Diagnosed with IDDM concludes that use the BCG vaccine does not alter the progressive decline in C-peptide levels or the clinical course of diabetes in newly diagnosed kids. (Diabetes Care 21:1691-1693, 1998) (4 October 1998)
  24. Improved Glycemic Control in Intensively Treated Type 1 Diabetic Patients Using Blood Glucose Meters With Storage Capability and Computer-Assisted Analyses concludes that use of a blood glucose meter with a memory, in conjunction with computerized diabetes management tools, can lead to improved glycemic control in adults. A1c levels dropped from an average of 7.0% before use to 6.3% after use of a meter with memory and computerized tools. (Diabetes Care 21:1694-1698, 1998) (4 October 1998)
  25. UK Prospective Diabetes Study (UKPDS) shows risk of complications of diabetes can be reduced dramatically in people with Type 2 diabetes. (20 September 1998)
  26. Alternative Medicine -- The Risks of Untested and Unregulated Remedies is an excellent editorial recently published in the New England Journal of Medicine. (20 September 1998)
  27. Studies Explore Abnormal Glucose Metabolism summarizes two recent studies, including the characteristics of diabetes in patients with cystic fibrosis. (20 September 1998)
  28. JDF announces new multimillion-dollar center to create a fast track for diabetes cure focused on islet cell transplantation. (12 September 1998)
  29. Compound in meat prevents Type 2 diabetes, study suggests. (6 September 1998)
  30. The British Medical Journal reports on Recent Advances in Diabetes. (30 August 1998)
  31. Study of teens with diabetes shows significantly higher albumin excretion in smokers compared with nonsmokers. (23 August 1998)
  32. Progestin-only contraceptives may increase risk Of Type 2 diabetes in women who had gestational diabetes. (16 Aug 1998)
  33. Data show anti-obesity drug Xenical improves glucose and lipid levels in people with Type 2 diabetes. (16 Aug 1998)
  34. The Islet Foundation reports that recent studies have demonstrated the safety of pig tissue for use in xenografts. (9 August 1998)
  35. Alarming rise in children's diabetes reported in Canada. (9 August 1998)
  36. Anyone interested in the direction of diabetes research in the United States should read the highlights of the recent Meeting of the Congressionally-Directed Diabetes Research Working Group (DRWG), as reported by Al Gorden of The Islet Foundation. (19 July 1998)
  37. The Juvenile Diabetes Foundation web site has been revamped. Be sure to read the 1998 Research Progress Report. (19 July 1998)
  38. Interested in inhaled insulin? Read our report from the ADA's 58th Scientific Sessions. (21 June 1998)
  39. Mersey Clinical Research Seeks Patients with Type 1 Diabetes for Study of Investigational Drug to Improve Metabolic Control.
  40. Novo Nordisk and Aradigm sign worldwide agreement to develop a pulmonary insulin delivery system. See also a streaming video presentation. (7 June 1998)
  41. Duke University Medical Center researchers report that antioxidants may reduce harmful complications of diabetes. (31 May 1998)
  42. Abstracts for the upcoming ADA Scientific Sessions in Chicago are available for searching. (31 May 1998)
  43. Islet Sheet Medical is developing a thin sheet bio-artificial pancreas as a treatment for Type 1 diabetes. (31 May 1998)
  44. The use of lispro insulin instead of Regular in an insulin pump improves control and reduces hypoglycemia. (24 May 1998)
  45. Puberty Linked to Accelerated Process of Early Kidney Damage in Diabetes. (24 May 1998)
  46. Research Offers Promise of Diabetes Cure is a television news report on islet cell research. (17 May 1998)
  47. Genentech Discontinues IGF-I Drug Development Effort In Type I and Type II Diabetes. (10 May 1998)
  48. The accuracy of some Home Blood Glucose Monitors has been studied again recently. (3 May 1998)
  49. According to the American Association of Clinical Endocrinologists, patients who follow their Intensive Diabetes Self-Management program delay major complications 15 years and add 5 years to their lives. (26 April 1998)
  50. The Islet Foundation reports on the International Workshop on Xenotransplantation, held in New York City, 18-20 March 1998. (12 April 1998)
  51. Berkeley team develops microscopic drug delivery system. (5 April 1998)
  52. Advances Toward the Implantable Artificial Pancreas for Treatment of Diabetes, published in the March 1998 issue of Diabetes Care, reviews the state of the art in developing an artificial pancreas. (15 Mar 1998)
  53. Neuropsychological Complications of IDDM in Children 2 Years After Disease Onset, published in the March 1998 issue of Diabetes Care, found that "... IDDM is associated with an increased risk of mild neuropsychological dysfunction." (15 Mar 1998)
  54. TRANSMEDICA announces clinical trial results for its laser blood sampling device. (1 Mar 1998)
  55. The Family Education Network reports on Sorbitol and Diarrhea in Young Children. (1 Mar 1998)
  56. JDF has published Concerns about Diabetes and Vaccines Questions and Answers which addresses the February 16, 1998 ABC News story which suggested that vaccines, depending on when they are administered, may increase or decrease the risk of developing Type 1 diabetes. (22 Feb 1998)
  57. Diabetic Kids Respond Better to ‘Can Do’ Than to Threats according to Nicole Palardy, MA, and colleagues at The University of Alabama. (15 Feb 98)
  58. Immune System Protein May Protect Against Insulin-Dependent Diabetes (15 Feb 98)
  59. Pancreatic Islet Transplants Set to Begin is from a Fall 1997 article published at Columbia University. (15 Feb 98)
  60. Replacing Cells to Fight Disease describes how scientists at Southwest Research Institute (SwRI), in collaboration with researchers at the Thomas E. Starzl Transplantation Institute (TESTI) at the University of Pittsburgh Medical Center, have completed initial work to develop a membrane system, or biomatrix, that may prove highly suitable for human islet cell encapsulation. (15 Feb 98)
  61. Transfer and Cloning of the Insulin Gene illustrates how the insulin gene is implanted into bacteria. (15 Feb 98)
  62. DRI Identifies Genetic Diabetes Link. (8 Feb 98)
  63. DRI Presents Results to International Pancreas and Islet Transplant Association (IPITA). (8 Feb 98)
  64. Technical Chemicals & Products, Inc is developing a non-invasive blood glucose meter that takes five minutes to produce a reading. (8 Feb 98)
  65. Jupiter (Florida) couple donates $5 million to Juvenile Diabetes Foundation (15 Jan 98)
  66. NASA program helps grow pancreatic tissue for transplant and attack diabetes. (4 Jan 98)

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