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Research News From 2004

  1. Navigating the future of continuous glucose monitoring includes a collection of presentations from the EASD meeting, held in Germany in September 2004. Notable presentations include: (26 December 2004)
    1. Freestyle Navigator Design and Technology Review by Dr. Ben Feldman, which reviews the continuous glucose sensor under development at Abbott Diabetes Care. (26 December 2004)
    2. Review of home use clinical trial: Clinical application of an interstitial fluid glucose monitor by Dr. Bruce Bode, which presents data on home use of Navigator. (26 December 2004)
    3. New perspectives on evaluating continuous monitors for clinical accuracy by Dr. William Clark, which offers excellent insight into how accuracy in continuous sensors should be judged. (26 December 2004)
    (26 December 2004)
  2. Lifetime glycaemic exposure predicts reduced coronary vasoreactivity in Type 1 diabetic subjects. (26 December 2004)
  3. Postprandial Hyperglycemia and Diabetes Complications. (26 December 2004)
  4. The Effect of Vitamin E on Endothelial Function of Micro- and Macrocirculation and Left Ventricular Function in Type 1 and Type 2 Diabetic Patients. (26 December 2004)
  5. Evidence for Accelerated Rates of Glutathione Utilization and Glutathione Depletion in Adolescents With Poorly Controlled Type 1 Diabetes. (26 December 2004)
  6. Periodontal Disease and Mortality in Type 2 Diabetes. (26 December 2004)
  7. Antigen-Specific FoxP3-Transduced T-Cells Can Control Established Type 1 Diabetes. (26 December 2004)
  8. Beta-Cell Function Following Human Islet Transplantation for Type 1 Diabetes. (26 December 2004)
  9. Pancreas-kidney transplantation in Japan: impact of cyclosporine on the development of immunosuppressive therapy. (26 December 2004)
  10. The use of cyclosporine in renal and pancreas transplantation. (26 December 2004)
  11. Embryonic stem cells: a promising tool for cell replacement therapy. Full text available in PDF. (26 December 2004)
  12. Effects of Exercise Training on Glucose Homeostasis. (26 December 2004)
  13. Ophthalmic glucose sensing: a novel monosaccharide sensing disposable and colorless contact lens. (26 December 2004)
  14. High glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells. (26 December 2004)
  15. Acetyl-L-Carnitine Improves Pain, Nerve Regeneration, and Vibratory Perception in Patients With Chronic Diabetic Neuropathy. (26 December 2004)
  16. Development of a Long-Acting Insulin Analog Using Albumin Fusion Technology. (26 December 2004)
  17. Utility of hemoglobin A1c in predicting diabetes risk. (26 December 2004)
  18. T1DBase, a community web-based resource for type 1 diabetes research. (26 December 2004)
  19. Diabetes vaccine trials to begin. See also New vaccine trials bring hope of cure for diabetes and Vaccine for Type 1 diabetes? (19 December 2004)
  20. Diabetes and stem cells according to: Jeremy J. Heit and Seung K. Kim: Embryonic stem cells and islet replacement in diabetes mellitus. (19 December 2004)
  21. Diabetes and stem cells according to: Susan Bonner Weir et al.: The pancreatic ductal epithelium serves as a potential pool of progenitor cells. (19 December 2004)
  22. Diabetes and stem cells according to: Matthias von Herrath and Dirk Homann: Islet regeneration needed for overcoming autoimmune destruction considerations on the pathogenesis of type 1 diabetes. (19 December 2004)
  23. Diabetes and stem cells according to: Joel F. Habener: A perspective on pancreatic stem/progenitor cells. (19 December 2004)
  24. Diabetes and stem cells according to: Shohta Kodama and Denise L. Faustman: Routes to regenerating islet cells: stem cells and other biological therapies for type 1 diabetes . (19 December 2004)
  25. Diabetes and stem cells according to: Vijayakumar Ramiya and Desmond Schatz: Islet replacement vs. regeneration: Hope or hype? (19 December 2004)
  26. Diabetes and stem cells according to: Timothy J. Kieffer et al.: Harnessing the gut to treat diabetes. (19 December 2004)
  27. Diabetes and stem cells according to: Gerald Schatten et al.: Can diabetes be cured by therapeutic cloning? (19 December 2004)
  28. Diabetes and stem cells according to: Andreas Lechner: Stem cells and regenerative medicine for the treatment of type 1 diabetes: the challenges lying ahead. (19 December 2004)
  29. Residual {beta}-Cell Function More than Glycemic Control Determines Abnormalities of the Insulin-Like Growth Factor System in Type 1 Diabetes. (19 December 2004)
  30. Poor in vitro maturation and pro-inflammatory cytokine response of dendritic cells in children at genetic risk of type 1 diabetes. (19 December 2004)
  31. Age-Dependent Influences on the Origins of Autoimmune Diabetes. (19 December 2004)
  32. Aspects of oxidative stress in children with Type 1 diabetes mellitus. (19 December 2004)
  33. Cerebral vasoreactivity in children and adolescents with type 1 diabetes mellitus. (19 December 2004)
  34. Telepaediatrics and diabetic retinopathy screening of young people with diabetes in Queensland. (19 December 2004)
  35. Type 1 diabetes in Jewish Ethiopian immigrants in Israel: HLA class II immunogenetics and contribution of new environment. (19 December 2004)
  36. Different HLA-DR-DQ and MHC class I chain-related gene A (MICA) genotypes in autoimmune and nonautoimmune gestational diabetes in a Swedish population. (19 December 2004)
  37. Visfatin: A Protein Secreted by Visceral Fat that Mimics the Effects of Insulin. See also Hormone in Fat Mimics Insulin. (19 December 2004)
  38. Animal cell transplants banned. (19 December 2004)
  39. Design and development of a scale measuring fear of complications in type 1 diabetes. (12 December 2004)
  40. Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACPI and sex. (12 December 2004)
  41. Parent responses to participation in genetic screening for diabetes risk. (12 December 2004)
  42. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. (12 December 2004)
  43. Prenatal and infant predictors of bone health: the influence of vitamin D. (12 December 2004)
  44. Brain glucose concentrations in patients with type 1 diabetes and hypoglycemia unawareness. (5 December 2004)
  45. Coronary Calcification in Long-term Type 1 Diabetic Patients - A Study with Multi Slice Spiral Computed Tomography. (5 December 2004)
  46. Diffusing capacity for carbon monoxide in children with type 1 diabetes. (5 December 2004)
  47. Type I diabetes mellitus and associated autoimmune diseases in the first-degree relatives of diabetic children: questionnaire based study. (5 December 2004)
  48. Latent autoimmune diabetes mellitus in children (LADC) with autoimmune thyroiditis and Celiac disease. (5 December 2004)
  49. IA-2 antibody epitopes and isotypes during the prediabetic process in siblings of children with type 1 diabetes. (5 December 2004)
  50. Scientists Generate Human Islet Precursor Cells In Culture. (5 December 2004)
  51. Retrovirally transferred genes inhibit apoptosis in an insulin-secreting cell line: implications for islet transplantation. (5 December 2004)
  52. Opinion: Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes. (5 December 2004)
  53. Regenerative medicine for pancreatic beta cells. (5 December 2004)
  54. High-sensitivity C-reactive protein and impaired coronary vasoreactivity in young men with uncomplicated type 1 diabetes. (5 December 2004)
  55. Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes. (5 December 2004)
  56. Improved Glycemic Control in Subjects with Atypical Diabetes Results from Restored Insulin Secretion, But Not Improved Insulin Sensitivity. (5 December 2004)
  57. The measurement of health-related quality of life (QOL) in paediatric clinical trials: a systematic review. Free full text available in HTML and PDF formats. (5 December 2004)
  58. Diet, Growth, and the Risk for Type 1 Diabetes in Childhood. (28 November 2004)
  59. Diabetes Incidence in 0- to 14-Year Age-Group in Italy. (28 November 2004)
  60. Scientists Generate Human Islet Precursor Cells in Culture from Cadaveric Insulin-producing Cells. (28 November 2004)
  61. Islet Graft Assessment in the Edmonton Protocol. (28 November 2004)
  62. Effect of Long-Term Administration of alpha-Lipoic Acid on Retinal Capillary Cell Death and the Development of Retinopathy in Diabetic Rats. (28 November 2004)
  63. Trial results give hope for control of type 1 diabetes, Big blow in war on diabetes, At-risk teen hopes to prevent diabetes and Vaccine may prevent onset of diabetes report on results of Pancreatic beta-Cell Function and Immune Responses to Insulin After Administration of Intranasal Insulin to Humans At Risk for Type 1 Diabetes. (28 November 2004)
  64. The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes. (21 November 2004)
  65. Protecting Pancreatic beta-cells. (21 November 2004)
  66. Bone mineral acquisition in adolescents with type 1 diabetes. (21 November 2004)
  67. Efficacy and Safety of Inhaled Insulin (Exubera) Compared With Subcutaneous Insulin Therapy in Patients With Type 1 Diabetes (free Medscape membership required). (21 November 2004)
  68. Effect of human umbilical cord blood cells on glycemia and insulitis in type 1 diabetic mice. (21 November 2004)
  69. A fourfold difference in the incidence of type 1 diabetes between Sweden and Lithuania but similar prevalence of autoimmunity. (21 November 2004)
  70. The prevalence of the metabolic syndrome and type 2 diabetes mellitus in children and adolescents. (21 November 2004)
  71. Premature Birth and Later Insulin Resistance. (21 November 2004)
  72. Adult pancreas generates multipotent stem cells and pancreatic and nonpancreatic progeny. (14 November 2004)
  73. Vitamin D receptor polymorphisms: are they really associated with type 1 diabetes? (14 November 2004)
  74. Abnormal proinsulin congeners as autoantigens that initiate the pathogenesis of Type 1 diabetes. (14 November 2004)
  75. Interstitial glucose kinetics in subjects with type 1 diabetes under physiologic conditions. (14 November 2004)
  76. Apoptosis and the beta-Cell in Type 1 and Type 2 Diabetes. (14 November 2004)
  77. beta-Cells in Type 2 Diabetes: A Loss of Function and Mass. (14 November 2004)
  78. Factors affecting C-peptide level during the first year of type 1 diabetes in children. (7 November 2004)
  79. Expression of beta-cell autoimmunity does not differ between potential dizygotic twins and siblings of patients with type 1 diabetes. (7 November 2004)
  80. Sonographic evaluation of bladder volume in diabetic children and adolescents compared with nondiabetic subjects. (7 November 2004)
  81. Oral glucose tolerance test in children and adolescents: Positives and pitfalls. (7 November 2004)
  82. Brief report: development and pilot testing of a coping questionnaire for children and adolescents with chronic health conditions. (7 November 2004)
  83. Health-related quality of life of children and adolescents with chronic illness--a two year prospective study. (7 November 2004)
  84. Pulmonary involvement in diabetes mellitus. (7 November 2004)
  85. IDDM1 and Multiple Family History of Type 1 Diabetes Combine to Identify Neonates at High Risk for Type 1 Diabetes. (31 October 2004)
  86. Exercise attenuates diabetes-induced ultrastructural changes in rat cardiac tissue. (31 October 2004)
  87. Efficacy and Safety of Inhaled Insulin (Exubera) Compared With Subcutaneous Insulin Therapy in Patients With Type 1 Diabetes. (31 October 2004)
  88. Intranasal Insulin Reduces Body Fat in Men but not in Women. (31 October 2004)
  89. Activated Protein C Preserves Functional Islet Mass After Intraportal Transplantation. (31 October 2004)
  90. Effects of Exenatide (Exendin-4) on Glycemic Control Over 30 Weeks in Sulfonylurea-Treated Patients With Type 2 Diabetes. (31 October 2004)
  91. Studies Underscore Soaring Childhood Obesity Epidemic. (31 October 2004)
  92. Physical Activity and Television Viewing in Relation to Risk of Undiagnosed Abnormal Glucose Metabolism in Adults. (31 October 2004)
  93. Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial. (24 October 2004)
  94. Gene-Nutrient Interactions in Type 1 Diabetes. (24 October 2004)
  95. Micronutrients and the risk of type 1 diabetes: vitamin D, vitamin E, and nicotinamide. (24 October 2004)
  96. Determinants of coronary artery calcification in diabetics with and without nephropathy. (24 October 2004)
  97. Albuminuria is evident in the early stages of diabetes onset: results from the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab). (24 October 2004)
  98. Early onset of subclinical atherosclerosis in young persons with type 1 diabetes. (17 October 2004)
  99. Insulin resistance is a risk factor for progression to Type 1 diabetes. (17 October 2004)
  100. Increased serum soluble leptin receptor levels in children and adolescents with type 1 diabetes mellitus. (17 October 2004)
  101. Lack of Effect of Vitamin D Administration during Pregnancy and Early Life on Diabetes Incidence in the Non-obese Diabetic Mouse. (17 October 2004)
  102. Enhancement of implantable glucose sensor function in vivo using gene transfer-induced neovascularization. (17 October 2004)
  103. A mouse model for studying intrahepatic islet transplantation. (17 October 2004)
  104. "Polypill" for Cardiovascular Disease Prevention. Also available in PDF format. (17 October 2004)
  105. Seasonality of type 1 diabetes mellitus in children and its modification by weekends and holidays: retrospective observational study. (10 October 2004)
  106. Waiting to inhale: noninjectable insulin, are we there yet? (10 October 2004)
  107. NIH Funds Centers to Study Islet Transplantation. See also UM to share millions for diabetes research, (10 October 2004)
  108. UCSF Stem Cell Research Focuses on Beta Cell Production. (10 October 2004)
  109. Transplantation as a therapeutic option for diabetic nephropathy. (10 October 2004)
  110. Silymarin protects pancreatic {beta}-cells against cytokine-mediated toxicity: Implication of c-Jun NH2-Terminal Kinase and Janus kinase/signal transducer and activator of transcription (STAT) pathways. Full text available in PDF format. (10 October 2004)
  111. Role of cyclooxygenase-2 in cytokine-induced beta -cell dysfunction and damage by isolated rat and human islets. Free full text available in PDF format. (10 October 2004)
  112. Pioglitazone and Sodium Salicylate Protect Human {beta}-Cells against Apoptosis and Impaired Function Induced by Glucose and Interleukin-1{beta}. (10 October 2004)
  113. Genetic and perinatal factors as risk for childhood type 1 diabetes. (10 October 2004)
  114. Prevention of type 1 diabetes by gene therapy. Free full text available in HTML and PDF formats. (10 October 2004)
  115. Distinct idiotypes of insulin autoantibody in autoimmune polyendocrine syndrome type 2 and childhood onset type 1 diabetes. (10 October 2004)
  116. A new way to look at eye complications in diabetes. (10 October 2004)
  117. Modelling the effect of alcohol in Type 1 diabetes. (10 October 2004)
  118. SEARCH for Diabetes in Youth: a multicenter study of the prevalence, incidence and classification of diabetes mellitus in youth. See also the SEARCH for Diabetes in Youth web site. (10 October 2004)
  119. Interventions to Improve Research Participants' Understanding in Informed Consent for Research. (10 October 2004)
  120. Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus. (3 October 2004)
  121. Cardiovascular Disease, Mortality, and Retinal Microvascular Characteristics in Type 1 Diabetes: Wisconsin Epidemiologic Study of Diabetic Retinopathy. (3 October 2004)
  122. Glucose tolerance of 2- to 5-yr-old offspring of diabetic mothers. (3 October 2004)
  123. Effect of Short-Term Hyperglycemia on Multifocal Electroretinogram in Diabetic Patients without Retinopathy. (3 October 2004)
  124. Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes. (3 October 2004)
  125. The number of unexpected HbA variants may be a greater problem in routine practice than is generally realized. (3 October 2004)
  126. Prospective Study of Social and Other Risk Factors for Incidence of Type 2 Diabetes in the Whitehall II Study. (3 October 2004)
  127. The occurrence and causes of registered blindness in diabetes patients in Arhus County, Denmark. (3 October 2004)
  128. The assessment of the level of growth factors in adolescents with type 1 diabetes mellitus and the beginning of diabetic microangiopathy. (3 October 2004)
  129. Effects of Vitamin E Supplementation on Intracellular Antioxidant Enzyme Production in Adolescents with Type 1 Diabetes and Early Microangiopathy. (3 October 2004)
  130. Acute renal failure due to drugs in diabetics patients. (3 October 2004)
  131. C-peptide: much more than a byproduct of insulin biosynthesis. (3 October 2004)
  132. Efficacy of Human Islet Isolation From the Tail Section of the Pancreas for the Possibility of Living Donor Islet Transplantation. (3 October 2004)
  133. Islet transplantation in patients with diabetes mellitus : choice of immunosuppression. (3 October 2004)
  134. Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets. (3 October 2004)
  135. Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice. (3 October 2004)
  136. Elevated C-Reactive Protein Levels in the Development of Type 1 Diabetes. (26 September 2004)
  137. Response of Human Islets to Isolation Stress and the Effect of Antioxidant Treatment. (26 September 2004)
  138. A Salen-Manganese Catalytic Free Radical Scavenger Inhibits Type 1 Diabetes and Islet Allograft Rejection. (26 September 2004)
  139. Artifactual Insulin Release From Differentiated Embryonic Stem Cells. (26 September 2004)
  140. Thiazolidinediones Reduce Endothelial Expression of Receptors for Advanced Glycation End Products. (26 September 2004)
  141. Meta-Analysis: Glycosylated Hemoglobin and Cardiovascular Disease in Diabetes Mellitus. See also High Blood Sugar Also Poses Risk to Heart, Better Blood Sugar Monitoring Benefits Diabetics, and Diabetics 'must test blood more'. (26 September 2004)
  142. Pancreatic beta-Cell Function and Immune Responses to Insulin After Administration of Intranasal Insulin to Humans At Risk for Type 1 Diabetes. (26 September 2004)
  143. Efficacy and Safety of Inhaled Insulin (Exubera) Compared With Subcutaneous Insulin Therapy in Patients With Type 2 Diabetes. (26 September 2004)
  144. The Treatment of Diabetic Gastroparesis With Botulinum Toxin Injection of the Pylorus. (26 September 2004)
  145. Type 1 Diabetes: A Cure in Sight? describes the research underway at Massachusetts General Hospital based on work by Dr. Denise Faustman. For more information, see Reversal of established autoimmune diabetes by restoration of endogenous beta cell function (free full text available as HTML and PDF), Islet regeneration during the reversal of autoimmune diabetes in NOD mice, Role of defective apoptosis in type 1 diabetes and other autoimmune diseases. This is the research being funded partially by the Iacocca Foundation. (26 September 2004)
  146. In Vivo and In Vitro Characterization of Insulin-Producing Cells Obtained From Murine Bone Marrow. (26 September 2004)
  147. Type 1 diabetes compromises plasma arachidonic and docosahexaenoic acids in newborn babies. (19 September 2004)
  148. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. Free full text available as HTML and PDF. See also Joslin researchers clarify mechanisms for beta-cell formation. (19 September 2004)
  149. Carnitine deficiency in children and adolescents with type 1 diabetes. (19 September 2004)
  150. Cytomegalovirus prevalence and transmission after islet allograft transplant in patients with type 1 diabetes mellitus. (19 September 2004)
  151. Descriptive study of onset diabetes mellitus type 1 patients and first degree families. (19 September 2004)
  152. Genetic susceptibility and immunological synapse in type 1 diabetes and thyroid autoimmune disease. (19 September 2004)
  153. Serious illness in childhood: the different threats of cancer and diabetes from a parent perspective. (19 September 2004)
  154. Postprandial plasma fructose level is associated with retinopathy in patients with type 2 diabetes. (19 September 2004)
  155. Centers Report Islet Transplant Results in Patients with Type 1 Diabetes. (12 September 2004)
  156. Transplantation of human umbilical cord blood cells improves glycemia and glomerular hypertrophy in type 2 diabetic mice. (12 September 2004)
  157. Reversal of diabetes in non-immunosuppressed rhesus macaques by intraportal porcine islet xenografts precedes acute cellular rejection. (12 September 2004)
  158. Infant feeding patterns in the Finnish type I diabetes prediction and prevention nutrition study cohort. (12 September 2004)
  159. Regulation of Net Hepatic Glycogenolysis and Gluconeogenesis during Exercise: Impact of Type 1 Diabetes. (12 September 2004)
  160. Ultrasonographic evaluation of atherosclerotic changes in carotid and brachial arteries in children with type 1 diabetes. (12 September 2004)
  161. C-Reactive Protein and Features of the Metabolic Syndrome in a Population-Based Sample of Children and Adolescents. (12 September 2004)
  162. Treatment strategies in patients with chronic renal disease: ACE inhibitors, angiotensin receptor antagonists, or both? (12 September 2004)
  163. Effect of photopheresis on lymphocyte population in children with newly diagnosed type 1 diabetes. (12 September 2004)
  164. Dr. George Eisenbarth offers commentary on Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes. Free full text available in both HTML and PDF format. (12 September 2004)
  165. Nocturnal hypertension: will control of nighttime blood pressure prevent progression of diabetic renal disease? (5 September 2004)
  166. Cholesterol metabolism in type 1 diabetes. (5 September 2004)
  167. Advances in Diabetes for the Millennium: Toward a Cure for Diabetes. (Free registration required) (5 September 2004)
  168. Improvement of the Quality of Diabetes Control and Decrease in the Concentrations of AGE-products in Patients with Type 1 and Insulin-treated Type 2 Diabetes mellitus - Results from a 10 Year-prospective, Population-based Survey on the Quality of Diabetes Care in Germany (JEVIN). (5 September 2004)
  169. Carnitine deficiency in children and adolescents with type 1 diabetes. (5 September 2004)
  170. Procurement of the human pancreas for pancreatic islet transplantation. (5 September 2004)
  171. Pancreatic Transplantation: Beta Cell Replacement. (5 September 2004)
  172. Relationship between antipsychotic medication treatment and new cases of diabetes among psychiatric inpatients. (5 September 2004)
  173. Infant diet and type 1 diabetes in China. (5 September 2004)
  174. Dietary habits and nutritional biomarkers in Italian type 1 diabetes families: evidence of unhealthy diet and combined-vitamin-deficient intakes. (5 September 2004)
  175. Is TAP2*0102 allele involved in insulin-dependent diabetes mellitus (type 1) protection? (5 September 2004)
  176. HLA DR phenotypic frequencies and genetic risk of Type 1 diabetes in west region of Algeria, Tlemcen. (5 September 2004)
  177. The genetics of HLA-associated disease. (5 September 2004)
  178. Type 1 diabetes mellitus in childhood: a matched case control study in Lancashire and Cumbria, UK. (29 August 2004)
  179. Temporary Preservation of beta-Cell Function by Diazoxide Treatment in Childhood Type 1 Diabetes. (29 August 2004)
  180. Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. See also Study identifies possible stem cells in pancreas. (29 August 2004)
  181. Regeneration of the heart in diabetes by selective copper chelation. (29 August 2004)
  182. Sugar-Sweetened Beverages, Weight Gain, and Incidence of Type 2 Diabetes in Young and Middle-Aged Women . See also full text in HTML and PDF formats. (29 August 2004)
  183. Statin use in Type 2 diabetes mellitus is associated with a delay in starting insulin. (29 August 2004)
  184. Population-Based Assessment of Familial Clustering of Diabetic Nephropathy in Type 1 Diabetes. (29 August 2004)
  185. Lens fluorescence and metabolic control in type 1 diabetic patients: a 14 year follow up study. (22 August 2004)
  186. Lens opacity in diabetics. Prevalence and association to visual deficiency and retinopathy. (22 August 2004)
  187. Causes of limited survival of microencapsulated pancreatic islet grafts. (22 August 2004)
  188. The increase in risk of diabetes mellitus from exposure to second-generation antipsychotic agents. (22 August 2004)
  189. In vivo gene transfer to pancreatic Beta cells by systemic delivery of adenoviral vectors. (22 August 2004)
  190. Peritoneal B cells govern the outcome of diabetes in non-obese diabetic mice. (22 August 2004)
  191. Stimulation of pancreatic islet neogenesis: a possible treatment for type 1 and type 2 diabetes. (15 August 2004)
  192. C-Peptide Can Help Diagnose Fulminant Type 1 Diabetes Mellitus offers CME credit. (15 August 2004)
  193. An increasing trend in the incidence of type 1 diabetes mellitus in children aged 0-14 years in Romania--ten years (1988-1997) EURODIAB study experience. (15 August 2004)
  194. Critique of Biological variation in HbA1c predicts risk of retinopathy and nephropathy in type 1 diabetes. (15 August 2004)
  195. Critique of Randomized trials of vitamin e in the treatment and prevention of cardiovascular disease. (15 August 2004)
  196. Maternal Plasma Ascorbic Acid (Vitamin C) and Risk of Gestational Diabetes Mellitus. (15 August 2004)
  197. Long-term progression of retinopathy after initiation of insulin therapy in Type 2 diabetes: an observational study. (15 August 2004)
  198. Prevalence of 20S proteasome, anti-nuclear and thyroid antibodies in young patients at onset of type 1 diabetes mellitus and the risk of autoimmune thyroiditis. (15 August 2004)
  199. Regulatory T cells and type 1 diabetes. (15 August 2004)
  200. Islet morphogenesis and stem cell markers. (8 August 2004)
  201. Islet-derived multipotential cells/progenitor cells. (8 August 2004)
  202. Directed differentiation of rhesus monkey ES cells into pancreatic cell phenotypes. Free full text in HTML or PDF format. (8 August 2004)
  203. Prediction of Autoantibody Positivity and Progression to Type 1 Diabetes: Diabetes Autoimmunity Study in the Young (DAISY). (8 August 2004)
  204. Low grade inflammation in juvenile obesity and type 1 diabetes associated with early signs of atherosclerosis. (8 August 2004)
  205. Absolute Risk of Childhood-Onset Type 1 Diabetes Defined by Human Leukocyte Antigen Class II Genotype: A Population-Based Study in the United Kingdom. (8 August 2004)
  206. Enterovirus-related type 1 diabetes mellitus and antibodies to glutamic acid decarboxylase in Japan. (8 August 2004)
  207. Introduction to pancreatic islet cell transplantation. (8 August 2004)
  208. NIH-Supported National Islet Transplantation Registry. (8 August 2004)
  209. Promoting islet cell function after transplantation. (8 August 2004)
  210. The Role of GLP-1 in the Regulation of Islet Cell Mass. (8 August 2004)
  211. Reflections on the 64th Scientific Sessions of the American Diabetes Association. (8 August 2004)
  212. Protein glycation: a firm link to endothelial cell dysfunction. (8 August 2004)
  213. Hypoglycemia-Dependent beta(2)-Adrenoceptor Downregulation: A Contributing Factor to Hypoglycemia Unawareness in Patients with Type-1 Diabetes? (8 August 2004)
  214. Female Children and Adolescents With Type 1 Diabetes Have More Pronounced Early Echocardiographic Signs of Diabetic Cardiomyopathy. Free full text available in HTML and PDF formats. (1 August 2004)
  215. Detection of Silent Myocardial Ischemia in Asymptomatic Diabetic Subjects. Free full text available in HTML and PDF formats. (1 August 2004)
  216. Proinflammatory Cytokines, Markers of Cardiovascular Risks, Oxidative Stress, and Lipid Peroxidation in Patients With Hyperglycemic Crises. (1 August 2004)
  217. Adiponectin and Leptin Concentrations May Aid in Discriminating Disease Forms in Children and Adolescents With Type 1 and Type 2 Diabetes. (1 August 2004)
  218. Reduced Forearm Blood Flow in Children and Adolescents With Type 1 Diabetes (Measured by Near-Infrared Spectroscopy). (1 August 2004)
  219. An ecological analysis of childhood-onset type 1 diabetes incidence and prevalence in Latin America. (1 August 2004)
  220. Male Sex Increases the Risk of Autoimmunity but not Type 1 Diabetes. (1 August 2004)
  221. Treatment of Type 1 Diabetes with Anti-T-cell Agents: From T-cell Depletion to T-cell Regulation. (1 August 2004)
  222. Generation of surrogate Beta cells from tissue stem cells. (1 August 2004)
  223. Simultaneous pancreas-kidney transplantation--an alternative option for the treatment of type 1 diabetes mellitus with renal failure. (1 August 2004)
  224. Evolving surgical strategies for pancreas transplantation. (1 August 2004)
  225. Canine and feline diabetes mellitus: nature or nurture? (1 August 2004)
  226. Diabetes Clinical Trials: What Is New at NIDDK? (25 July 2004)
  227. The Prove It Study: Is It Really a Landmark Study or Another Piece of a Very Important Puzzle? (25 July 2004)
  228. Generation of Surrogate Beta Cells from Tissue Stem Cells. (25 July 2004)
  229. Stem-cell therapy for diabetes mellitus. (25 July 2004)
  230. Risks and Side Effects of Islet Transplantation. (25 July 2004)
  231. Evolving Surgical Strategies for Pancreas Transplantation. (25 July 2004)
  232. Treatment of Type 1 Diabetes with Anti-T-cell Agents: From T-cell Depletion to T-cell Regulation. (25 July 2004)
  233. A 14-year prospective study of autonomic nerve function in Type 1 diabetic patients: association with nephropathy. (25 July 2004)
  234. C-reactive protein, its role in inflammation, Type 2 diabetes and cardiovascular disease, and the effects of insulin-sensitizing treatment with thiazolidinediones. (25 July 2004)
  235. Advances in Diabetes Through Animal-related Research. (18 July 2004)
  236. A new look at viruses in type 1 diabetes. (18 July 2004)
  237. Pancreatic islet and stem cell transplantation: new strategies in cell therapy of diabetes mellitus. Free full text available in PDF format. (18 July 2004)
  238. Assessment of human pancreatic islets after long distance transportation. (18 July 2004)
  239. Type 1 diabetes-related antibodies in the fetal circulation: prevalence and influence on cord insulin and birth weight in offspring of mothers with type 1 diabetes. (18 July 2004)
  240. Precursor frequencies of T-cells reactive to insulin in recent onset type 1 diabetes mellitus. (18 July 2004)
  241. Genetic screening for individuals at high risk for type 1 diabetes in the general population using HLA Class II alleles as disease markers. A comparison between three European populations with variable rates of disease incidence. (18 July 2004)
  242. Serum antibodies to the major proteins found in cow's milk of Iranian patients with Type 1 diabetes mellitus. (18 July 2004)
  243. Molecular basis of predisposition to develop type 1 diabetes mellitus in North Indians. (18 July 2004)
  244. Type 1 diabetes genetic susceptibility encoded by HLA DQB1 genes in Romania. (18 July 2004)
  245. Pre-pubertal onset of type 1 diabetes and appearance of retinopathy. (11 July 2004)
  246. C-peptide: new findings and therapeutic implications in diabetes. (11 July 2004)
  247. Impact of hypoglycemia and diabetes on CNS: correlation of mitochondrial oxidative stress with DNA damage. (11 July 2004)
  248. Declining incidence of severe retinopathy and persisting decrease of nephropathy in an unselected population of Type 1 diabetes-the Linkoping Diabetes Complications Study. (11 July 2004)
  249. Retinopathy and microalbuminuria in type II diabetic patients. (11 July 2004)
  250. The effects of a combined strength and aerobic exercise program on glucose control and insulin action in women with type 2 diabetes. (11 July 2004)
  251. Nutritional concerns in the diabetic athlete. (11 July 2004)
  252. Macrovascular disease after simultaneous pancreas and kidney transplantation.. (11 July 2004)
  253. Diabetes control and complications: the role of glycated haemoglobin, 25 years on. (4 July 2004)
  254. Perinatal factors and development of islet autoimmunity in early childhood: the diabetes autoimmunity study in the young. (4 July 2004)
  255. Higher maternal age at delivery, and lower birth orders are associated with increased risk of childhood type 1 diabetes mellitus. (4 July 2004)
  256. Anti-GAD-positive patients with Type 1 diabetes mellitus have higher prevalence of autoimmune thyroiditis than anti-GAD-negative patients with Type 1 and Type 2 diabetes mellitus. Free full text available in PDF format. (4 July 2004)
  257. Elevated iron indices in patients with diabetes. (4 July 2004)
  258. Prospective study of post-partum thyroid immune dysfunctions in type 1 diabetic women and in a healthy control group living in a mild iodine deficient area. (4 July 2004)
  259. A central role for inflammation in the pathogenesis of diabetic retinopathy. (4 July 2004)
  260. Epidemiology of diabetic retinopathy and macular oedema: a systematic review. (4 July 2004)
  261. Angiopoietic factors and retinopathy in pregnancies complicated with Type 1 diabetes. (4 July 2004)
  262. Follow-up of kidney biopsies in normoalbuminuric patients with type 1 diabetes. (4 July 2004)
  263. Islet Regeneration Research Accelerates New Discoveries Pose Intriguing New Challenges. (4 July 2004)
  264. First UK survey of paediatric type 2 diabetes and MODY. (4 July 2004)
  265. Animal Models to Study Adult Stem Cell-derived, in Vitro-generated Islet Implantation. (4 July 2004)
  266. Development of a novel digestion chamber for human and porcine islet isolation. (4 July 2004)
  267. The natural autoantibody repertoire and autoimmune disease. (4 July 2004)
  268. Natural antibodies prevent in vivo transmission of porcine islet-derived endogenous retrovirus to human cells. (4 July 2004)
  269. Nonhuman primate models for islet transplantation in type 1 diabetes research. (4 July 2004)
  270. Nonhuman primate models in type 1 diabetes research. (4 July 2004)
  271. Neuroendocrine Immuno-ontogeny of the Pathogenesis of Autoimmune Disease in the Nonobese Diabetic (NOD) Mouse. (4 July 2004)
  272. Evaluation of a Type 2 Diabetes Screening Protocol in an Urban Pediatric Clinic. (4 July 2004)
  273. Disturbed Eating Behavior and Eating Disorders in Preteen and Early Teenage Girls With Type 1 Diabetes. (27 June 2004)
  274. Pramlintide for the treatment of insulin-requiring diabetes mellitus: rationale and review of clinical data. (27 June 2004)
  275. A Multinational Comparison of Complications Assessment in Type 1 Diabetes. (27 June 2004)
  276. Nationwide, Prospective Registration of Type 1 Diabetes in Children Aged <15 Years in Norway 1989ľ1998. (27 June 2004)
  277. Type 1 Diabetes Among Sardinian Children Is Increasing. (27 June 2004)
  278. Pancreas Transplantation Improves Vascular Disease in Patients With Type 1 Diabetes. (27 June 2004)
  279. Cure of Overt Diabetes in NOD Mice by Transient Treatment With Anti-Lymphocyte Serum and Exendin-4. (27 June 2004)
  280. Eligibility of diabetic patients for islet transplantation alone. (20 June 2004)
  281. Successful Simultaneous Islet-Kidney Transplantation using a Steroid-free Immunosuppression: Two-Year Follow-up. (20 June 2004)
  282. Disseminated periportal fatty degeneration after allogeneic intraportal islet transplantation in a patient with type 1 diabetes mellitus: a case report. (20 June 2004)
  283. Half of Islet Transplant Patients Insulin-Free at 1 Year. (20 June 2004)
  284. Analysis of donor factors affecting human islet isolation with current isolation protocol. (20 June 2004)
  285. There are no differences in pretransplant characteristics of individuals receiving simultaneous pancreas-kidney transplant and individuals with type 1 diabetes mellitus receiving living-related kidney transplant. (20 June 2004)
  286. C-peptide and central nervous system complications in diabetes. (20 June 2004)
  287. Type 1 diabetic neuropathy and C-peptide. (20 June 2004)
  288. Molecular and cellular effects of C-peptide--new perspectives on an old peptide. (20 June 2004)
  289. Hemoglobin A1c level and future cardiovascular events among women. (20 June 2004)
  290. Prevalence of diabetes mellitus in Norway. (20 June 2004)
  291. Coexistence of IgE-Mediated Allergy and Type 1 Diabetes in Childhood. (20 June 2004)
  292. Rotavirus-specific T-cell responses in young prospectively followed-up children. (20 June 2004)
  293. Reduced response of retinal vessel diameters to flicker stimulation in patients with diabetes. (20 June 2004)
  294. Effects of lipid-altering treatment in diabetes mellitus and the metabolic syndrome. (20 June 2004)
  295. Strategies in ongoing clinical trials to reduce cardiovascular disease in patients with diabetes mellitus and insulin resistance. (20 June 2004)
  296. Do stressful life events cause type 1 diabetes? (13 June 2004)
  297. Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus - a new surrogate measure of non-progression? (13 June 2004)
  298. Brief Communication: Early Appearance of Islet Autoantibodies Predicts Childhood Type 1 Diabetes in Offspring of Diabetic Parents. (13 June 2004)
  299. Development of Islet Cell Autoantibodies and Type 1 Diabetes. (13 June 2004)
  300. Class I and II HLA Genes Are Associated with Susceptibility and Age at Onset in Finnish Families with Type 1 Diabetes. (13 June 2004)
  301. Angiotensin-converting enzyme gene polymorphism and lipid profiles in Kuwaiti children with type 1 diabetes. (13 June 2004)
  302. Clinical presentation of childhood type 1 diabetes mellitus in the Al-Madina region of Saudi Arabia. (13 June 2004)
  303. Use of Sertoli cell transplants to provide local immunoprotection for tissue grafts. (13 June 2004)
  304. Glycohemoglobin (A1C) distribution in school children: Results from a school-based screening program. (13 June 2004)
  305. Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women. See also Fructose, weight gain, and the insulin resistance syndrome (also in PDF format) and Not All Sugars Are Equal, at Least When it Comes to Weight Gain and Health. (13 June 2004)
  306. In vitro-generation of surrogate islets from adult stem cells. (6 June 2004)
  307. Generation of Insulin-Producing Cells from Stem Cells for Cell Replacement Therapy of Type 1 Diabetes. Full text available in PDF format. (6 June 2004)
  308. Prevention of Type 1A Diabetes: Update. (6 June 2004)
  309. Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents. (6 June 2004)
  310. Enterovirus infections with beta-cell tropic strains are frequent in siblings of children diagnosed with type 1 diabetes children and in association with elevated levels of GAD65 antibodies. (6 June 2004)
  311. Thoughts on the Pathogenesis of Type 1 Diabetes and on the Arrest of Autoimmune Beta-Cell Destruction by Peptide p277 Vaccination. (6 June 2004)
  312. Selected Abstracts from the Annual Meeting of the Israel Association of Diabetes. (6 June 2004)
  313. First UK survey of paediatric type 2 diabetes and MODY. (6 June 2004)
  314. Obesity and the Metabolic Syndrome in Children and Adolescents. (6 June 2004)
  315. A randomized trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX). (30 May 2004)
  316. The Prevalence of Diabetic Retinopathy Among Adult Type 1 Diabetic Persons in the United States. See also The Prevalence of Diabetic Retinopathy Among Adults in the United States and Development and progression of diabetic retinopathy in patients with Type 1 diabetes who are positive for GAD autoantibody. (30 May 2004)
  317. Influence of Autonomic Neuropathy on QTc Interval Lengthening During Hypoglycemia in Type 1 Diabetes. (30 May 2004)
  318. Clinical Characteristics of Children Diagnosed With Type 1 Diabetes Through Intensive Screening and Follow-Up. (30 May 2004)
  319. Patient Satisfaction and Glycemic Control After 1 Year With Inhaled Insulin (Exubera) in Patients With Type 1 or Type 2 Diabetes. (30 May 2004)
  320. Reduced Mortality Associated With the Use of ACE Inhibitors in Patients With Type 2 Diabetes. (30 May 2004)
  321. Biological Variation in HbA1c Predicts Risk of Retinopathy and Nephropathy in Type 1 Diabetes. See also 2 tests better to gauge diabetes. (30 May 2004)
  322. Vascular endothelium and inflammatory process, in patients with combined Type 2 diabetes mellitus and coronary atherosclerosis: the effects of vitamin C. (30 May 2004)
  323. In vitro-generation of surrogate islets from adult stem cells. (30 May 2004)
  324. Abstracts from the upcoming Scientific Sessions of the ADA are online. We have a page with selected abstracts. (23 May 2004)
  325. The significance of the prepubertal diabetes duration for the development of retinopathy and nephropathy in patients with type 1 diabetes. (23 May 2004)
  326. Inhaled insulin: May prove to be a panacea. See also responses to this editorial. (23 May 2004)
  327. Coxsackie B virus serology and Type 1 diabetes mellitus: a systematic review of published case-control studies. (23 May 2004)
  328. Left ventricular dysfunction in normotensive Type 1 diabetic patients: the impact of autonomic neuropathy. (23 May 2004)
  329. Development and progression of diabetic retinopathy in patients with Type 1 diabetes who are positive for GAD autoantibody. (23 May 2004)
  330. The value of the Rydel-Seiffer tuning fork as a predictor of diabetic polyneuropathy compared with a neurothesiometer. (23 May 2004)
  331. Decreased stiffness at the ankle joint in patients with long-term Type 1 diabetes. (23 May 2004)
  332. Cytokine profile in children during the first 3 months after the diagnosis of type 1 diabetes. (23 May 2004)
  333. Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity. See also 'Underappreciated' Immune Cells May Play Important Role in Progression of Type 1 Diabetes, Joslin Researchers Find. (23 May 2004)
  334. Diabetes Mellitus and Risk of Alzheimer Disease and Decline in Cognitive Function. See also Possible Mechanism for Link Between Diabetes and Alzheimer's Disease Discovered, Diabetes Linked To Increased Risk Of Alzheimer's In Long-term Study and Diabetes Linked to Increased Risk of Alzheimer's in Long-Term Study. (23 May 2004)
  335. Renal functional reserve in patients with Type 1 diabetes mellitus. (23 May 2004)
  336. An increase in insulin sensitivity and basal beta-cell function in diabetic subjects treated with pioglitazone in a placebo-controlled randomized study. (23 May 2004)
  337. Cardiac and vascular function in adolescents and young adults with type 1 diabetes. (16 May 2004)
  338. Insulin-producing Pancreatic Cells Are Replenished By Duplication. (16 May 2004)
  339. CRP and IL-6 concentrations are associated with poor glycemic control despite preserved beta-cell function during the first year after diagnosis of type 1 diabetes. (16 May 2004)
  340. Improved insulin secretory function and reduced chemotactic properties after tissue culture of islets from type 1 diabetic patients. (16 May 2004)
  341. Skeletal involvement in patients with diabetes mellitus. (16 May 2004)
  342. Autoantibodies as predictors of disease. (16 May 2004)
  343. Islet-cell antibodies and type 1 diabetes after treatment with interferon-alpha. (16 May 2004)
  344. Type 2 diabetes in grandparents and birth weight in offspring and grandchildren in the ALSPAC study. (16 May 2004)
  345. A randomised trial of nicotinamide and vitamin E in children with recent onset type 1 diabetes (IMDIAB IX) concludes that "the use of nicotinamide alone or in combination with Vit E along with intensive insulin therapy is able to preserve baseline C-peptide secretion for up to two years after diagnosis." Compare to European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes. (9 May 2004)
  346. The May 6, 2004 issue of the journal nature features Pancreatic insulin factories: Beta to beta and Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. See also Insulin-Producing Pancreatic Cells Are Replenished by Duplication. (9 May 2004)
  347. Autoimmunity to islet proteins in children diagnosed with new-onset diabetes. (9 May 2004)
  348. beta-Cell Secretory Function and CD25 + Lymphocyte Subsets In the Early Stage of Type 1 Diabetes Mellitus. (9 May 2004)
  349. Autoimmune diabetes is blocked in Stat4-deficient mice. See also Disruption of a Gene May Prevent Type 1 Diabetes, University of Virginia Researchers Find. (9 May 2004)
  350. Up-Regulation of CD1d Expression Restores the Immunoregulatory Function of NKT Cells and Prevents Autoimmune Diabetes in Nonobese Diabetic Mice. (9 May 2004)
  351. Immunosuppressive and anti-inflammatory action of antioxidants in rat autoimmune diabetes. (9 May 2004)
  352. History of diabetes mellitus and risk of prostate cancer in physicians. (9 May 2004)
  353. Skin denervation in type 2 diabetes: correlations with diabetic duration and functional impairments. (9 May 2004)
  354. Aradigm's lead product up in air. See also Aradigm and Novo Nordisk Release Interim Analysis of Initial Pulmonary Insulin Phase 3 Trial. (2 May 2004)
  355. Normal weight promotes remission and low number of islet antibodies prolong the duration of remission in Type 1 diabetes. (2 May 2004)
  356. Pancreas transplant alone. (2 May 2004)
  357. The effect of spironolactone, cilazapril and their combination on albuminuria in patients with hypertension and diabetic nephropathy is independent of blood pressure reduction: a randomized controlled study. (2 May 2004)
  358. Acute, local effects of iontophoresed insulin and C-peptide on cutaneous microvascular function in Type 1 diabetes mellitus. (2 May 2004)
  359. Islet Cell Autoimmunity in a Triethnic Adult Population of the Third National Health and Nutrition Examination Survey. (2 May 2004)
  360. A clinically orientated approach increases the efficiency of screening for latent autoimmune diabetes in adults (LADA) in a large clinic-based cohort of patients with diabetes onset over 50 years. (2 May 2004)
  361. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Full text available in HTML and PDF formats. (2 May 2004)
  362. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity. Full text available in HTML and PDF formats. (2 May 2004)
  363. Type 1 diabetes mellitus in Catalonia: chronic complications and metabolic control ten years after onset.. (2 May 2004)
  364. Anti-insulin activity in IgG-fractions from children with newly-diagnosed type 1 diabetes and negative for insulin autoantibodies. (2 May 2004)
  365. Insulin Sensitivity in the Offspring of Women With Type 1 and Type 2 Diabetes. (2 May 2004)
  366. Prevalence of Hepatic Steatosis After Islet Transplantation and Its Relation to Graft Function. (2 May 2004)
  367. Activating Mutations in the Gene Encoding the ATP-Sensitive Potassium-Channel Subunit Kir6.2 and Permanent Neonatal Diabetes. See also Neonatal Diabetes May Sometimes Be Treatable With Sulfonylureas, Breakthrough for diabetic babies and 'Old-fashioned' pills cure baby born diabetic. (2 May 2004)
  368. Cerebral dysfunction in type 1 diabetes: effects of insulin, vascular risk factors and blood-glucose levels. (25 April 2004)
  369. Predictors for the development of microalbuminuria and macroalbuminuria in patients with type 1 diabetes: inception cohort study. Full text available in PDF format. (25 April 2004)
  370. Continued increase in the incidence of childhood Type 1 diabetes in a population-based Australian sample (1985-2002). (25 April 2004)
  371. Genotypic and phenotypic differences between Arabian and Scandinavian women with gestational diabetes mellitus. (25 April 2004)
  372. Depleting Anti-cd4 Monoclonal Antibody Cures New-onset Diabetes, Prevents Recurrent Autoimmune Diabetes, And Delays Allograft Rejection In Nonobese Diabetic Mice. (18 April 2004)
  373. Homeostatic Expansion of T Cells during Immune Insufficiency Generates Autoimmunity. See also Diabetes Type 1 could be caused by being too clean. (18 April 2004)
  374. Health and economic impact of combining metformin with nateglinide to achieve glycemic control: Comparison of the lifetime costs of complications in the U.K. (18 April 2004)
  375. Redefining the clinical remission period in children with type 1 diabetes. (11 April 2004)
  376. Clustering of autoimmune disease in parents of siblings from the Type 1 diabetes Warren repository. (11 April 2004)
  377. A novel per-oral insulin formulation: proof of concept study in non-diabetic subjects. (11 April 2004)
  378. Follow-up Report on the Diagnosis of Diabetes Mellitus. (11 April 2004)
  379. Childhood Vaccination and Type 1 Diabetes. (4 April 2004)
  380. Longer breastfeeding is an independent protective factor against development of type 1 diabetes mellitus in childhood. (4 April 2004)
  381. High Incidence of Childhood Type 1 Diabetes in the Avalon Peninsula, Newfoundland, Canada. (4 April 2004)
  382. Type 1 diabetes: recent developments. Also in PDF format. See also the Rapid Responses. (4 April 2004)
  383. DCCT: The Study That Forever Changed the Nature of Treatment of Type 1 Diabetes. (4 April 2004)
  384. Mortality in young people admitted to hospital for diabetes: database study. Also in PDF format. (4 April 2004)
  385. Genetic prediction of type 1 diabetes in a population with low frequency of HLA risk genotypes and low incidence of the disease (the DIABFIN study). (4 April 2004)
  386. Gender differences in GAD antibody - positive diabetes mellitus in relation to age at onset, C-peptide and other endocrine autoimmune diseases. (4 April 2004)
  387. TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. (4 April 2004)
  388. Diabetes Susceptibility Gene Discovered. (4 April 2004)
  389. Cost Analysis of Human Islet Transplantation for the Treatment of Type 1 Diabetes in the Swiss-French Consortium GRAGIL. (4 April 2004)
  390. London team reports diabetes breakthrough. (4 April 2004)
  391. Animal models of spontaneous autoimmune diabetes: notes on their relevance to the human disease. (4 April 2004)
  392. Inhalation of Insulin in Dogs: Assessment of Insulin Levels and Comparison to Subcutaneous Injection. (4 April 2004)
  393. Evidence of Functional Impairment of Syngeneically Transplanted Mouse Pancreatic Islets Retrieved from the Liver. (4 April 2004)
  394. Psychological impact of childhood islet autoantibody testing in families participating in the BABYDIAB study. (28 March 2004)
  395. Clustering of autoimmune disease in parents of siblings from the Type 1 diabetes Warren repository. (28 March 2004)
  396. Quantitative Ultrasound Measurements in Children and Adolescents with: Type 1 Diabetes. (28 March 2004)
  397. A novel per-oral insulin formulation: proof of concept study in non-diabetic subjects. (28 March 2004)
  398. European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes. See also Nicotinamide Failed to Prevent Onset of Type 1 Diabetes Among High Risk Patients. (21 March 2004)
  399. GAD65 antibody isotypes and epitope recognition during the prediabetic process in siblings of children with type I diabetes. (21 March 2004)
  400. Antibodies to GAD65 Epitopes at Diagnosis and Over the First 10 years of Clinical Type 1 Diabetes Mellitus. (21 March 2004)
  401. Glycemic control, oxidative stress, and lipid profile in children with type 1 diabetes mellitus. (21 March 2004)
  402. Neurocognitive correlates of type 1 diabetes mellitus in childhood. (21 March 2004)
  403. Evaluation of sensorimotor polyneuropathy in children and adolescents with type I diabetes: associations with microalbuminuria and retinopathy. (21 March 2004)
  404. Vascular leucocyte adhesion molecules unaltered in the human retina in diabetes. (21 March 2004)
  405. Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. See also Hormone linked to osteoporosis. (21 March 2004)
  406. Glycosylated Hemoglobin, Cardiovascular, and Renal Outcomes in a Pharmacist-Managed Clinic. (21 March 2004)
  407. Optical glucose sensor holds promise for patients. (21 March 2004)
  408. Insulin-producing cells found in unexpected places. (21 March 2004)
  409. Swedes link stress to diabetes in children. (21 March 2004)
  410. Cell therapies for type 1 diabetes mellitus. (14 March 2004)
  411. Insulin expressing cells from differentiated embryonic stem cells are not beta cells. (14 March 2004)
  412. Xenotransplantation: Researchers Target Pig Cells For Animal-to-Human Islet Cell Transplantation. (14 March 2004)
  413. Possible correlation between diabetes and hearing loss. (14 March 2004)
  414. Specific HLA-DRB and -DQB Alleles and Haplotypes Confer Disease Susceptibility or Resistance in Bahraini Type 1 Diabetes Patients. (14 March 2004)
  415. Induction of protective therapy for autoimmune diseases by targeted DNA vaccines encoding pro-inflammatory cytokines and chemokines. (14 March 2004)
  416. Hydroxy-methylglutaryl-coenzyme a reductase inhibition improves endothelial dysfunction in type-1 diabetes. (14 March 2004)
  417. INGAP Continues to Look Promising. (14 March 2004)
  418. Effect of antidiabetic medications on microalbuminuria in patients with type 2 diabetes. (14 March 2004)
  419. Effect of Gender on the Counterregulatory Responses to Exercise after Antecedent Hypoglycemia in Type-1 Diabetes. (7 March 2004)
  420. U of M researchers a step further in Type 1 diabetes treatment. See also Researchers A Step Further In Type 1 Diabetes Treatment; Single Infusion Of Islet Cells Surpasses Previous Success and UCSF/U. Minnesota researchers mark new islet transplant milestone. (29 February 2004)
  421. Growth data in large series of 587 children and adolescents with type 1 diabetes mellitus. (29 February 2004)
  422. No Evidence for Significant Transdifferentiation of Bone Marrow Into Pancreatic ▀-Cells In Vivo. (29 February 2004)
  423. Consequences on ▀-Cell Function and Reserve After Long-Term Pancreas Transplantation. (29 February 2004)
  424. Geographical Variation in Risk HLA-DQB1 Genotypes for Type 1 Diabetes and Signs of ▀-Cell Autoimmunity in a High-Incidence Country. (29 February 2004)
  425. Association of Human Endogenous Retrovirus K-18 Polymorphisms With Type 1 Diabetes. Free full text available in HTML or PDF format. (29 February 2004)
  426. Isolation of enterovirus strains from children with preclinical Type 1 diabetes. (29 February 2004)
  427. Relationship between the incidence of type 1 diabetes and enterovirus infections in different European populations: Results from the EPIVIR project. (29 February 2004)
  428. Paternal phenotype is associated with microalbuminuria in young adults with Type 1 diabetes mellitus of short duration. (29 February 2004)
  429. Association of the VEGF Gene With Proliferative Diabetic Retinopathy But Not Proteinuria in Diabetes. Free full text available in HTML or PDF format. (29 February 2004)
  430. Glycemic Exposure Is Associated With Reduced Pulmonary Function in Type 2 Diabetes. (29 February 2004)
  431. Mechanisms of genetic susceptibility to type I diabetes: beyond HLA. (22 February 2004)
  432. Diabetic retinopathy. (22 February 2004)
  433. Management and outcome of sight-threatening diabetic retinopathy in pregnancy. (22 February 2004)
  434. Surgical management of chronic pancreatitis and the role of islet cell autotransplantation. (22 February 2004)
  435. Insulin-producing Cells Found In A Variety Of Tissues In Diabetes. (22 February 2004)
  436. Auditory brainstem evoked responses in insulin-dependent (ID) and non-insulin-dependent (NID) diabetic subjects with normal hearing. (22 February 2004)
  437. Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes. (22 February 2004)
  438. Preventative biology of type 1 diabetes: implications for clinical preventative studies. (15 February 2004)
  439. International parallels in leukaemia and diabetes epidemiology. See also International Incidence of Acute Lymphoblastic Leukemia and Type 1 Diabetes Linked. (15 February 2004)
  440. Persistence of impaired pancreatic beta-cell function in children treated for acute lymphoblastic leukaemia. (15 February 2004)
  441. Seminars in Transplantation From the Emory Transplant Center - Transplantation Options for the Diabetic Patient. (15 February 2004)
  442. Transplantation of Cultured Islets from Two-Layer Preserved Pancreases in Type 1 Diabetes with Anti-CD3 Antibody. (15 February 2004)
  443. Adult porcine islets produce MCP-1 and recruit human monocytes in vitro. (15 February 2004)
  444. Despite Advance in Cloning, Scientists Are Tempering Hope With Reality. (Free registration required) (15 February 2004)
  445. The emergence of type 2 diabetes in childhood. (15 February 2004)
  446. The epidemiology of Type 1 diabetes mellitus is not the same in young adults as in children. (8 February 2004)
  447. White blood count as a predictor of glucose tolerance and insulin sensitivity. (8 February 2004)
  448. Immunologic and genetic aspects of latent autoimmune diabetes in the adult. (8 February 2004)
  449. All-cause mortality in diabetic patients treated with combinations of sulfonylureas and biguanides. (8 February 2004)
  450. The Steno Diabetes Study. (8 February 2004)
  451. Hepatocyte Growth Factor Gene Therapy for Pancreatic Islets in Diabetes: Reducing the Minimal Islet Transplant Mass Required in a Glucocorticoid-Free Rat Model of Allogeneic Portal Vein Islet Transplantation . See also Gene therapy technique could aid islet transplants for diabetes, says Pittsburgh study. (8 February 2004)
  452. Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health. (8 February 2004)
  453. Prevention of Type 1 Diabetes: Position Statement of the American Diabetes Association. (1 February 2004)
  454. Insulin Secretion in Type 1 Diabetes. (1 February 2004)
  455. Is Presence of Islet Autoantibodies at Birth Associated With Development of Persistent Islet Autoimmunity? (1 February 2004)
  456. Maternal Anxiety Associated With Newborn Genetic Screening for Type 1 Diabetes. (1 February 2004)
  457. Insulin-like growth factor I has a direct effect on glucose and protein metabolism, but no effect on lipid metabolism in type 1 diabetes. (1 February 2004)
  458. Mechanisms of beta cell death during restricted and unrestricted enterovirus infection. (1 February 2004)
  459. Isolation of enterovirus strains from children with preclinical Type 1 diabetes. (1 February 2004)
  460. Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells. (1 February 2004)
  461. The occurrence of type 1 diabetes in patients with dermatitis herpetiformis and their first-degree relatives. (1 February 2004)
  462. Low prevalence of autoimmune diabetes markers in a mixed ethnic population of Singaporean diabetics. (1 February 2004)
  463. HLA haplotypes associated with type 1 diabetes mellitus in North Indian children. (1 February 2004)
  464. Risk Factors for Coronary Heart Disease in Type 1 Diabetic Patients in Europe: The EURODIAB Prospective Complications Study. (1 February 2004)
  465. Dietary Antioxidant Intake and Risk of Type 2 Diabetes. (1 February 2004)
  466. You can read the JDRF Position Paper on Embryonic Stem Cells. (25 January 2004)
  467. The Belgrade childhood diabetes study: association of infections and vaccinations on diabetes in childhood. (25 January 2004)
  468. Elevated levels of plasma homocysteine in hypertensive patients with diabetes mellitus. (25 January 2004)
  469. Gestational diabetes mellitus clusters in families with a history of diabetes. (25 January 2004)
  470. Poor Control of Risk Factors for Vascular Disease Among Adults With Previously Diagnosed Diabetes. (25 January 2004)
  471. Drug Prevents Diabetes Recurrence After Islet Cell Transplantation discusses The novel anti-inflammatory agent lisofylline prevents autoimmune diabetic recurrence after islet transplantation, reported last week. (25 January 2004)
  472. Can Amylin Analogue Lead To Better Diabetes Control? (25 January 2004)
  473. Alterations in bone characteristics associated with glycemic control in adolescents with type 1 diabetes mellitus. (18 January 2004)
  474. The Finnish Diabetes Prevention Study (DPS): Lifestyle Intervention and 3-Year Results on Diet and Physical Activity. (18 January 2004)
  475. The Relation of Retinal Vessel Caliber to the Incidence and Progression of Diabetic Retinopathy: The Wisconsin Epidemiologic Study of Diabetic Retinopathy. (18 January 2004)
  476. Relationship between blood glucose control, pathogenesis and progression of diabetic nephropathy. See also Decline of Glomerular Function Increases When Glycated Haemoglobin Steadily Higher Than 7.5%. (18 January 2004)
  477. Nerve conduction in children suffering insulin dependent diabetes mellitus. (18 January 2004)
  478. Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets. (18 January 2004)
  479. The novel anti-inflammatory agent lisofylline prevents autoimmune diabetic recurrence after islet transplantation. (18 January 2004)
  480. Insulin sensitivity in physically fit and unfit children of parents with Type 2 diabetes. (18 January 2004)
  481. Impaired Glucose Tolerance and Reduced beta-Cell Function in Overweight Latino Children with a Positive Family History for Type 2 Diabetes. (18 January 2004)
  482. Changes in cardiac repolarization during clinical episodes of nocturnal hypoglycaemia in adults with Type 1 diabetes. (11 January 2004)
  483. Stem cells: a promising source of pancreatic islets for transplantation in type 1 diabetes. (11 January 2004)
  484. Kinetics of diabetes-associated autoantibodies after sequential intraportal islet allograft associated with kidney transplantation in type 1 diabetes. (11 January 2004)
  485. Prevention of type 1 diabetes: what have we achieved? What should we say and propose next to families? (11 January 2004)
  486. The long-term renal and retinal outcome of childhood-onset Type 1 diabetes. (11 January 2004)
  487. Dermal enhancement: bacterial products on intact skin induce and augment organ-specific autoimmune disease. See also Doubts on vaccine patch for children. (11 January 2004)
  488. Coffee Consumption and Risk for Type 2 Diabetes Mellitus. (11 January 2004)
  489. Duration of breast feeding and bovine serum albumin antibody levels in type 1 diabetes: a case-control study. (4 January 2004)
  490. Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient. See also Virus 'halts decline of diabetes'. (4 January 2004)
  491. Dietary Magnesium Intake in Relation to Plasma Insulin Levels and Risk of Type 2 Diabetes in Women. (4 January 2004)
  492. Girls at Five Are Intrinsically More Insulin Resistant Than Boys: The Programming Hypotheses Revisited-The EarlyBird Study (EarlyBird 6). (4 January 2004)
  493. 'I'm amazed I've been able to come off injections': patients' perceptions of genetic testing in diabetes. (4 January 2004)

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