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Research News From 2005

    25 December 2005

  1. Can we slow the rising incidence of childhood-onset autoimmune diabetes? The overload hypothesis.
  2. Use of antimicrobials and risk of type 1 diabetes in a population-based mother-child cohort.
  3. Long-term mortality in a nationwide cohort of childhood-onset type 1 diabetic patients in Norway.
  4. A Low Brain Serotonergic Neurotransmission in Children With Type 1 Diabetes Detected Through the Intensity Dependence of Auditory-Evoked Potentials.

    18 December 2005

  5. Environmental factors related to the induction of beta-cell autoantibodies in 1-yr-old healthy children.
  6. Is immunity in diabetic patients influencing the susceptibility to infections? Immunoglobulins, complement and phagocytic function in children and adolescents with type 1 diabetes mellitus.
  7. Cytoplasmic islet cell antibodies remain valuable in defining risk of progression to type 1 diabetes in subjects with other islet autoantibodies.
  8. The role of the diet as a risk factor for the development and progression of diabetic nephropathy. Free full text available in Portuguese in HTML and PDF formats.
  9. Characterization of human islet-like structures generated from pancreatic precursor cells in culture.
  10. Autoreactive CD8 T cells associated with {beta} cell destruction in type 1 diabetes.
  11. The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multi-center collaborative study in Japan. Free full text available in PDF format.
  12. The relevance of international consortia in studies on the pathogenesis of type 1 diabetes: the role of ET1DGN.
  13. Pig cell diabetes treatment debated. See also Benson-Pope Speech: Xenotransplantation Report, NZ backs animal transplants for humans, Animal transplants into humans given go ahead and, Camps split over divisive transplants.

    11 December 2005

  14. Dose-response relationship of an oral insulin spray in six patients with type 1 diabetes: A single-center, randomized, single-blind, 5-way crossover study.
  15. Unfavorable effect of type 1 and type 2 diabetes on maternal and fetal essential fatty acid status: a potential marker of fetal insulin resistance.
  16. New-onset diabetes and antihypertensive drugs.
  17. Tmem27: A cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation.

    4 December 2005

  18. Low Levels of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 in Patients with Newly Diagnosed Type 1 Diabetes.
  19. Osteoprotegerin serum levels in children with type 1 diabetes: a potential modulating role in bone status.
  20. The impact of diabetes mellitus on skeletal health: an established phenomenon with inestablished causes?
  21. Increased vulnerability of newly forming beta cells to cytokine-induced cell death.
  22. Facilitating Physiologic Self-Regeneration: A Step Beyond Islet Cell Replacement. Free full text available in PDF format.
  23. Intraperitoneal alginate-encapsulated neonatal porcine islets in a placebo-controlled study with 16 diabetic cynomolgus primates.
  24. Endocrine self and gut non-self intersect in the pancreatic lymph nodes.
  25. New ways in which GLP-1 can regulate glucose homeostasis. Free full text available in HTML and PDF formats. The PDF contains a simple yet excellent diagram.
  26. Sleep loss and the development of diabetes: a review of current evidence.
  27. Thyroid gland diseases in adult patients with diabetes mellitus.
  28. Further Evidence that Alzheimer's Is a Type of Diabetes. See also Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?, Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease [second abstract], Evidence Grows That Alzheimer's Is A Type Of Diabetes, and Insulin Study Backs Theory Alzheimer's May Be Type of Diabetes.
  29. Award for diabetes breakthrough. See also Queen's Anniversary Prize for Pioneering Exeter Diabetes Researchers.
  30. Early nephropathy in type 1 diabetes: a new perspective on who will and who will not progress.
  31. Transgenic expression and recovery of biologically active recombinant human insulin from Arabidopsis thaliana seeds. See also SemBioSys reports positive plant produced insulin data.
  32. D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus.

    20 November 2005

  33. The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. See also the discussion at BioCritique.
  34. The 'accelerator hypothesis': relationship between weight, height, body mass index and age at diagnosis in a large cohort of 9,248 German and Austrian children with type 1 diabetes mellitus.

    13 November 2005

  35. Epidemiological Association between Some Dietary Habits and the Increasing Incidence of Type 1 Diabetes Worldwide.
  36. Would blockage of cytokines improve the outcome of pancreatic islet transplantation?
  37. Stem cells in the treatment of diabetes.
  38. Update on regulatory issues in pancreatic islet transplantation.
  39. Autoimmune destruction of pancreatic Beta cells.
  40. Gene Therapy for Type 1 Diabetes.
  41. Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes.
  42. Immunotherapeutic approaches to prevent, ameliorate, and cure type 1 diabetes.
  43. Heterogeneity of vitamin D receptor gene association with celiac disease and type 1 diabetes mellitus.
  44. T-cell assays to determine disease activity and clinical efficacy of immune therapy in type 1 diabetes.
  45. Outcomes of pancreas transplants for patients with type 2 diabetes mellitus.

    6 November 2005

  46. Prevalence of impaired fasting glucose and its relationship with cardiovascular disease risk factors in US adolescents, 1999-2000.
  47. {beta}-cell Function, Insulin Sensitivity and Glucose Tolerance in Obese Diabetic and Nondiabetic Adolescents and Young Adults. Free full text available in PDF format.
  48. Emerging drugs for diabetic nephropathy.
  49. Fetal and neonatal exposure to nicotine in Wistar rats results in increased beta cell apoptosis at birth and postnatal endocrine and metabolic changes associated with type 2 diabetes.
  50. Stevioside does not cause increased basal insulin secretion or beta-cell desensitization as does the sulphonylurea, glibenclamide: Studies in vitro.

    30 October 2005

  51. Islet Cell Hormonal Responses to Hypoglycemia After Human Islet Transplantation for Type 1 Diabetes.
  52. Gene therapy for type 1 diabetes: a proposal to move to the next level.
  53. Color visual evoked potentials in children with type 1 diabetes: relationship to metabolic control.
  54. Decreased Endogenous Secretory Advanced Glycation End Product Receptor in Type 1 Diabetic Patients: Its possible association with diabetic vascular complications.
  55. Increased risk of diabetes among relatives of female insulin-treated patients diagnosed at 15-34 years of age.
  56. Exposure to Farming Environments in Early Life and Type 1 Diabetes: A Case-Control Study.
  57. Complex analysis of the physical metabolic and genetic state in children of mothers with type 1 diabetes.
  58. Risk of Diabetic Nephropathy in Type 1 Diabetes Is Associated With Functional Polymorphisms in RANTES Receptor Gene (CCR5). Free full text available in HTML and PDF formats.
  59. Fat food for a bad mood. Could we treat and prevent depression in Type 2 diabetes by means of omega-3 polyunsaturated fatty acids? A review of the evidence.
  60. High Incidence of Diabetes in Men With Sleep Complaints or Short Sleep Duration.

    23 October 2005

  61. Nicotinamide protected first-phase insulin response (FPIR) and prevented clinical disease in first-degree relatives of type-1 diabetics.
  62. Boost for type 1 vaccine research.
  63. Enteroviruses: New findings on the role of enteroviruses in type 1 diabetes.
  64. Plasma homocysteine and microvascular and macrovascular complications in type 1 diabetes: a cross-sectional nested case-control study.
  65. MMR Vaccine is Safe, International Team Affirms.

    16 October 2005

  66. Dr. Denise Faustman offers a Fall 2005 Update on her work to cure type 1 diabetes.
  67. Islet neogenesis: A potential therapeutic tool in type 1 diabetes.
  68. Immunological mechanisms associated with long-term remission of human type 1 diabetes.
  69. How robust is the evidence for viruses in the induction of type 1 diabetes?
  70. Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes.
  71. Soluble, dimeric HLA DR4-peptide chimeras: An approach for detection and immunoregulation of human type-1 diabetes.
  72. The impact of diabetes on cognition: What can be learned from rodent models?
  73. Incidence of end-stage renal disease in patients with type 1 diabetes.
  74. School dinners and markers of cardiovascular health and type 2 diabetes in 13-16 year olds: cross sectional study.
  75. Normal Fasting Plasma Glucose Levels and Type 2 Diabetes in Young Men.

    9 October 2005

  76. Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?
  77. The thymus way in pathogenesis and prevention of type 1 diabetes.
  78. A two year observational study of nicotinamide and intensive insulin therapy in patients with recent onset type 1 diabetes mellitus.
  79. Altered glycemia and brain-update and potential relevance to the aging brain.
  80. Absence of breast-feeding is associated with the risk of type 1 diabetes: a case-control study in a population with rapidly increasing incidence.
  81. Mechanisms of endothelial dysfunction with development of type 1 diabetes mellitus: Role of insulin and C-peptide.
  82. Hypoxic stress in diabetic pregnancy contributes to impaired embryo gene expression and defective development by inducing oxidative stress.
  83. Pancreatic Stem Cells: A Glimmer of Hope for Diabetes? Also available in PDF format.
  84. Latent autoimmune diabetes in adults (LADA) should be less latent.

    1 October 2005

  85. Mothers' Experiences of Serious Life Events Increase the Risk of Diabetes-Related Autoimmunity in Their Children.
  86. Hospitalization because of diabetes and bereavement: a national cohort study of parents who lost a child.
  87. A human beta-cell line for transplantation therapy to control type 1 diabetes. See also Human Beta-cell Line Offers Hope for Type 1 Diabetes Breakthrough, 'Reversibly immortalized' cell line that can supply large amounts of insulin-producing human beta-cells, Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes, and Good-bye Insulin Shots.
  88. Signals From the Embryonic Mouse Pancreas Induce Differentiation of Human Embryonic Stem Cells Into Insulin-Producing beta-Cell–Like Cells.
  89. UCSD Study Sheds New Light on Insulin's Role in Blocking Fat Breakdown in Patients with Type II Diabetes. See also Chronically high levels of insulin may block specific hormones that trigger energy release into the body.
  90. The Role of Autoimmunity at Diagnosis of Type 1 Diabetes in the Development of Thyroid and Celiac Disease and Microvascular Complications.
  91. Modulation of the Renal Response to ACE Inhibition by ACE Insertion/Deletion Polymorphism During Hyperglycemia in Normotensive, Normoalbuminuric Type 1 Diabetic Patients.
  92. Antiangiogenic Endostatin Peptide Ameliorates Renal Alterations in the Early Stage of a Type 1 Diabetic Nephropathy Model.
  93. Maternal consumption of dairy products during pregnancy and lactation, and the development of cow's milk antibodies in the offspring.
  94. New test predicts damage from diabetes.
  95. The socioeconomic correlates of global complication prevalence in type 1 diabetes (T1D): A multinational comparison.

    25 September 2005

  96. Are there advantages with U-Albumin/U-Creatinine ratios compared with U-Albumin in monitoring diabetes?
  97. Increased Plasma Pro-B-Type Natriuretic Peptide in Infants of Women with Type 1 Diabetes.
  98. In vivo treatment with glucagon-like peptide 1 promotes the graft function of fetal islet-like cell clusters in transplanted mice.
  99. Glucagon-Like Peptide-1 as a Treatment Option for Type 2 Diabetes and Its Role in Restoring Beta-Cell Mass.
  100. Immunomodulation with human recombinant autoantigens.
  101. Production of a recombinant cholera toxin B subunit-insulin B chain peptide hybrid protein by Brevibacillus choshinensis expression system as a nasal vaccine against autoimmune diabetes.
  102. Gene therapy for diabetes mellitus in rats by intramuscular injection of lentivirus containing insulin gene.

    18 September 2005

  103. Up-regulation Of Advanced-glycated Products Receptors In The Brain Of Diabetic Rats Is Prevented By Antioxidant Treatment. Free full text available in PDF format.
  104. Use of Long-Term Microdialysis Subcutaneous Glucose Monitoring in the Management of Neonatal Diabetes.
  105. Gluatamic Acid Decarboxylase Autoantibody Prevalence and Association with HLA Genotype in Patients with Younger-Onset Type 1 Diabetes and Proliferative Diabetic Retinopathy.
  106. Insulin - a primary autoantigen in type 1 diabetes?
  107. The pancreatic islet endothelial cell: Emerging roles in islet function and disease.
  108. Morphological and functional changes in the diabetic peripheral nerve: using diagnostic ultrasound and neurosensory testing to select candidates for nerve decompression.
  109. Surgical Decompression in Lower-Extremity Diabetic Peripheral Neuropathy.
  110. Surgical treatment of peripheral neuropathy: outcomes from 100 consecutive decompressions.
  111. Lilly moves forward with inhaled insulin.

    11 September 2005

  112. Early Nutrition and its later Consequences is a 256-page downloadable PDF with several articles related to nutrition and diabetes, including Trial To Reduce IDDM In The Genetically At Risk (Nutritional Primary Prevention Of Type 1 Diabetes) Early Nutrition And Later Diabetes Risk (page 142), Is Type 1 Diabetes A Disease Of The Gut Immune System Triggered By Cow's Milk Insulin? (page 151), Gluten-free Diet In Subjects At Risk For Type 1 Diabetes: A Tool For Delaying Progression To Clinical Disease? (page 157), and Dietary Compliance In Diabetes Prevention Project In Finland (page 189). Be patient while the large PDF downloads.
  113. Differential changes in brain glucose metabolism during hypoglycaemia accompany loss of hypoglycaemia awareness in men with type 1 diabetes mellitus. An [(11)C]-3-O-methyl-D: -glucose PET study.
  114. The Glu23Lys polymorphism in KCNJ11 and impaired hypoglycaemia awareness in patients with type 1 diabetes.
  115. Novel predictors of overt nephropathy in subjects with type 1 diabetes. A nested case control study from the Pittsburgh Epidemiology of Diabetes Complications cohort.
  116. Exenatide Augments First and Second Phase Insulin Secretion in Response to Intravenous Glucose in Subjects with Type 2 Diabetes. Free full text available in PDF format.

    4 September 2005

  117. The November 2005 issue of Diabetes, Obesity and Metabolism has five articles on the topic of unlocking the opportunity of tight glycaemic control, focusing primarily on the potential for inhaled insulin to achieve better results.
    1. Unlocking the opportunity of tight glycaemic control: Far from goal.
    2. Unlocking the opportunity of tight glycaemic control: Innovative delivery of insulin via the lung.
    3. Unlocking the opportunity of tight glycaemic control: Inhaled insulin: clinical efficacy.
    4. Unlocking the opportunity of tight glycaemic control: Inhaled insulin: safety.
    5. Unlocking the opportunity of tight glycaemic control: Promise ahead: the role of inhaled insulin in clinical practice.
  118. The rising incidence of childhood type 1 diabetes in New South Wales, 1990–2002. See also Childhood diabetes on the rise in NSW.
  119. Early nutrition and later diabetes risk.
  120. Ecological Approaches to Self-Management: The Case of Diabetes.
  121. Ultrasound evaluation of vascular complications in pancreas transplant recipients.
  122. Islet beta cell function in latent autoimmune diabetes in adults with islet cell antibodies.
  123. Xenotransplantation of porcine neonatal islets of Langerhans and Sertoli cells: a 4-year study.
  124. Protection of NOD Mice From Type 1 Diabetes After Oral Inoculation with Vaccinia Viruses Expressing Adjuvanted Islet Autoantigens.
  125. Mortality study of policies on insured lives with diabetes mellitus known at time of issue.

    28 August 2005

  126. Strict Glycemic Control Slashes CVD Risk in Type 1 Diabetes.
  127. The Effect of Insulin Antibodies on the Metabolic Action of Inhaled and Subcutaneous Insulin.
  128. What are disease perceptions and subjective treatment goals of insulin treated diabetic patients? Free full text available in PDF format.
  129. Where is the Cure?
  130. UCSF drug continues to fend off progression of type 1 diabetes.
  131. Prevalence of Type 1 diabetes in New Zealanders aged 0-24 years.
  132. Identifying risk of type 1 diabetes.
  133. How to make pancreatic beta cells - prospects for cell therapy in diabetes.
  134. Gastrointestinal stem cells. I. Pancreatic stem cells.
  135. Differentiation of Human Liver-Derived, Insulin-Producing Cells Toward the beta-Cell Phenotype.
  136. Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans. Full text available in PDF format. See also Insulin sensitivity gets a kick out of SOCS-7.
  137. The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy. See also Malfunctioning bone marrow cells sabotage nerve cells in diabetes.
  138. Genetic testing for glucokinase mutations in clinically selected patients with MODY: a worthwhile investment. Free full text available in PDF format.

    21 August 2005

  139. Are children with type 1 diabetes immunocompromised? Also available in PDF format.
  140. Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes. Free full text available in PDF format.
  141. Familial clustering of beta-cell autoimmunity in initially non-diabetic children.
  142. Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates.
  143. Trying To Predict the Future for People with Diabetes: A Tough but Important Task.
  144. Clinical Outcomes and Cost-Effectiveness of Strategies for Managing People at High Risk for Diabetes.
  145. Type 2 Diabetes: Problems in the Furnace.
  146. DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice.
  147. Abstracts for the upcoming EASD conference are online. Due to the way the web site that hosts the abstracts is configured, we are not able to create reliable links to specific abstracts.

    14 August 2005

  148. Circulating acylated and total ghrelin and galanin in children with insulin-treated type 1 diabetes: relationship to insulin therapy, metabolic control and pubertal development.
  149. Therapeutic targets for the prevention of type 1 diabetes mellitus.
  150. Islet transplantation in type I diabetes mellitus.
  151. Estimation of lipoperoxidative damage and antioxidant status in diabetic children: Relationship with individual antioxidants.
  152. The DIabetic REtinopathy Candesartan Trials (DIRECT) Programme: baseline characteristics.
  153. Increased serum adiponectin levels in type 1 diabetic patients with microvascular complications.
  154. Developments in the prediction of type 1 diabetes mellitus, with special reference to insulin autoantibodies.
  155. HLA DR/DQ alleles and risk of type I diabetes in childhood: a population-based case-control study.

    7 August 2005

  156. Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis.
  157. Rapid Destruction of Encapsulated Islet Xenografts by NOD Mice is CD4-Dependent and Facilitated by B-cells: Innate Immunity and Autoimmunity Do Not Play Significant Roles.
  158. Hematopoietic stem cell transplantation prevents diabetes in NOD mice but does not contribute to significant islet cell regeneration once disease is established.
  159. Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells.
  160. Differentiation of in vitro-modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells.
  161. Prevention of type 1 diabetes with major histocompatibility complex-compatible and nonmarrow ablative hematopoietic stem cell transplants.
  162. Pancreatic islet cell transplantation: progress in the clinical setting.
  163. Regenerative medicine of the pancreatic beta cells.
  164. From stem cells to insulin-producing cells: towards a bioartificial endocrine pancreas.
  165. Identification and expansion of pancreatic stem/progenitor cells.
  166. Challenges of primate embryonic stem cell research.
  167. Characterization of mouse spleen cells by subtractive proteomics. Free full text available in PDF format.
  168. The favorable outcome of human islet transplantation in Korea: experiences of 10 autologous transplantations.
  169. Health-related quality of life after pancreatic islet transplantation: a longitudinal study.
  170. Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes. Free full text available in HTML and PDF formats.
  171. Towards a medically approved technology for alginate-based microcapsules allowing long-term immunoisolated transplantation.

    31 July 2005

  172. Consequence or coincidence? The occurrence, pathogenesis and significance of autoimmune manifestations after viral vaccines.
  173. How can the innate immune system influence autoimmunity in type 1 diabetes and other autoimmune disorders?
  174. Effect of Low-Dose Insulin Treatment on Body Weight and Physical Development in Children and Adolescents at Risk for Type 1 Diabetes.
  175. Discordant Trends in Microvascular Complications in Adolescents With Type 1 Diabetes From 1990 to 2002.
  176. Youth and Parent Satisfaction With Clinical Use of the GlucoWatch G2 Biographer in the Management of Pediatric Type 1 Diabetes.
  177. Efficacy of Inhaled Insulin in Patients With Type 2 Diabetes not Controlled With Diet and Exercise.
  178. ADA: Lung Function Still a Problem with Inhaled Insulin.
  179. Donor Islet Endothelial Cells Participate in Formation of Functional Vessels Within Pancreatic Islet Grafts.
  180. Generation of insulin-producing cells from stem cells.
  181. Viral IL-10-Mediated Immune Regulation in Pancreatic Islet Transplantation.
  182. Serum Pepsinogen I, An Early Marker Of Pernicious Anemia In Patients With Type 1 Diabetes. Full text available in PDF format.
  183. Association of angiotensin-converting enzyme DD genotype with 24-h blood pressure abnormalities in normoalbuminuric children and adolescents with Type 1 diabetes.
  184. Increased plasma markers of inflammation and endothelial dysfunction and their association with microvascular complications in Type 1 diabetic patients without clinically manifest macroangiopathy.
  185. Metabolic Syndrome in Type 1 Diabetes: Association with diabetic nephropathy and glycemic control (the FinnDiane study).
  186. Annual Incidence and Clinical Characteristics of Type 2 Diabetes in Children as Detected by Urine Glucose Screening in the Tokyo Metropolitan Area.
  187. Autoantibodies to Autonomic Nerves Associated With Cardiac and Peripheral Autonomic Neuropathy.
  188. Should kids be used in clinical research?
  189. Subcutaneous microdialysis before and after an oral glucose tolerance test: a method to determine insulin resistance in the subcutaneous adipose tissue in diabetes mellitus.
  190. Type 2 Diabetes Mellitus as a Conformational Disease. Full text available in HTML and PDF formats.
  191. The effect of manipulation of basal pulsatile insulin on insulin action in Type 2 diabetes.
  192. Effects of liraglutide (NN2211), a long-acting GLP-1 analogue, on glycaemic control and bodyweight in subjects with Type 2 diabetes.
  193. Personal and family history of autoimmune diabetes mellitus and susceptibility to young-adult-onset Hodgkin lymphoma.

    24 July 2005

  194. Differences in Type I Diabetes Mellitus of Young Adults with and without Thyroid Autoimmunity.
  195. B cells as key contributors in determining the level of immune responses -B-cell-targeted therapy in patients with autoimmune diseases.
  196. Cochlear changes in patients with type 1 diabetes mellitus.
  197. Protein-induced diabetes. Study Identifies Fat-Secreted Protein Linked To Insulin Resistance.
  198. Coffee consumption and risk of type 2 diabetes: a systematic review.
  199. The effects of plasma insulin and glucose on myocardial blood flow in patients with type 1 diabetes mellitus.
  200. Association of socioeconomic position with insulin resistance among children from Denmark, Estonia, and Portugal: cross sectional study. Free full text available in PDF format.
  201. The Early Natural History of Nephropathy in Type 1 Diabetes: III. Predictors of 5-Year Urinary Albumin Excretion Rate Patterns in Initially Normoalbuminuric Patients.
  202. Inhibitors of advanced glycation end product formation and neurovascular dysfunction in experimental diabetes.
  203. Pfizer Exubera Inhaled Insulin To Go To FDA Endocrine Committee Sept. 8.
  204. Oral administration of a cholera toxin B subunit-insulin fusion protein produced in silkworm protects against autoimmune diabetes.

    17 July 2005

  205. Carotid Intima-Media Thickness: An Index for Subclinical Atherosclerosis in Type 1 Diabetes.
  206. Vitamin D and type 1 diabetes mellitus: state of the art.
  207. In insulin-autoantibody-positive children from the general population, antibody affinity identifies those at high and low risk.
  208. Diabetes-associated HLA genotypes affect birthweight in the general population.
  209. Neonatal diabetes mellitus: from understudy to center stage.
  210. Incidence of Type 1 diabetes in children in Caceres, Spain, during 1988-1999.
  211. Effect of Insulin with Concurrent Amino Acid Infusion on Protein Metabolism in Rapidly Growing Pubertal Children with Type 1 Diabetes.
  212. The Role of Intramyocellular Lipids During Hypoglycemia in Patients With Intensively Treated Type 1 Diabetes.
  213. Increased accumulation of skin advanced glycation end-products precedes and correlates with clinical manifestation of diabetic neuropathy.
  214. Inflammation and the etiology of type 2 diabetes.

    10 July 2005

  215. Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience.
  216. Alloreactivity Against Repeated HLA Mismatches of Sequential Islet Grafts Transplanted in Non-Uremic Type 1 Diabetes Patients.
  217. New sources of pancreatic beta-cells.
  218. Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets.
  219. Wheat protein-induced proinflammatory T helper 1 bias in mesenteric lymph nodes of young diabetes-prone rats.
  220. Markers of endothelial dysfunction in the prediction of coronary artery disease in Type 1 diabetes. The Pittsburgh Epidemiology of Diabetes Complications Study.
  221. Degradation products of proteins damaged by glycation, oxidation and nitration in clinical type 1 diabetes.
  222. Biokinetics of buccal spray insulin in patients with type 1 diabetes.

    3 July 2005

  223. Seasonality of month of birth of children and adolescents with type 1 diabetes mellitus in homogenous and heterogeneous populations.
  224. Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse.
  225. Five-Year Follow-Up After Clinical Islet Transplantation.
  226. Use of Inhaled Insulin in a Basal/Bolus Insulin Regimen in Type 1 Diabetic Subjects.
  227. Epidemiology of type I diabetes mellitus among Arab children.
  228. Psychosocial and Socioeconomic Risk Factors for Premature Death in Young People With Type 1 Diabetes.
  229. Impact of Overweight on Chronic Microvascular Complications in Type 1 Diabetic Patients.
  230. The changing epidemiology of diabetic microangiopathy in type 1 diabetes.
  231. Relation of C-Reactive Protein to Insulin Resistance and Cardiovascular Risk Factors in Youth.
  232. Effects of Irbesartan on Intracellular Antioxidant Enzyme Expression and Activity in Adolescents and Young Adults With Early Diabetic Angiopathy.
  233. Predictors of 5-Year Urinary Albumin Excretion Rate Patterns in Initially Normoalbuminuric Patients.

    26 June 2005

  234. Insulin Needs after CD3-Antibody Therapy in New-Onset Type 1 Diabetes. See also European Researchers Find That Anti-CD3 Antibody Preserves Beta Cell Function in Type 1 Diabetes Patients.
  235. The therapeutic potential of tumor necrosis factor for autoimmune disease: a mechanistically based hypothesis.
  236. How viral infections affect the autoimmune process leading to type 1 diabetes.
  237. Increasing trend of childhood type 1 diabetes in Franche-Comte (France): analysis of age and period effects from 1980 to 1998.
  238. Late diabetes complications and non-dipping phenomenon in patients with Type 1 diabetes.
  239. Brain metabolite changes on proton magnetic resonance spectroscopy in children with poorly controlled type 1 diabetes mellitus.
  240. The effect of pancreatic islet transplantation on progression of diabetic retinopathy and neuropathy.
  241. Vitamin D and diabetes.
  242. IFN-gamma Low Production Capacity in Type 1 Diabetes Mellitus Patients at Onset of Disease.

    19 June 2005

  243. Does autoantigen administration inhibit recurrence of type 1 diabetes in transplanted islets?
  244. Fetal origins of insulin resistance and obesity.
  245. Insights from the developing world: thrifty genotypes and thrifty phenotypes.

    12 June 2005

  246. Influence of diabetes on peripheral bone mineral density in men: a controlled study.
  247. Childhood diabetes in the Czech Republic: a steady increase in incidence.
  248. Antibody Response to Inhaled Insulin in Patients with Type 1 or Type 2 Diabetes. An Analysis of Initial Phase II and III Inhaled Insulin (Exubera) Trials and a Two-Year Extension Trial.

    5 June 2005

  249. Transplantation and Islet Topics.
  250. Effect of insulin on plasma vascular endothelial growth factor in children with new onset diabetes.
  251. TH1/TH2 cytokine secretion of first degree relatives of T1DM patients.
  252. Longitudinal observation of enterovirus and adenovirus in stool samples from Norwegian infants with the highest genetic risk of type 1 diabetes.
  253. Bacteria of food and human intestine are the most possible sources of the gad-trigger of type 1 diabetes.
  254. Real-time glucose sensing using transdermal fluid under continuous vacuum pressure in children with type 1 diabetes.
  255. Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study.
  256. Genetic Analysis Of Families With Autoimmune Diabetes And Thyroiditis: Evidence For Common And Unique Genes.

    29 May 2005

  257. Continuous Glucose Monitoring in Interstitial Subcutaneous Adipose Tissue and Skeletal Muscle Reflects Excursions in Cerebral Cortex.
  258. Environmental Triggers for Type 1 Diabetes.
  259. Therapeutic Neovascularization Using Cord Blood–Derived Endothelial Progenitor Cells for Diabetic Neuropathy.
  260. Association between a protein polymorphism in the start codon of the vitamin D receptor gene and severe diabetic retinopathy in C-peptide-negative type 1 diabetes.
  261. Frequency, Severity, and Morbidity of Hypoglycemia Occurring in the Workplace in People With Insulin-Treated Diabetes.
  262. Dose-Response Relationship of Oral Insulin Spray in Healthy Subjects.
  263. Long-Term Impact of Breast-Feeding on Body Weight and Glucose Tolerance in Children of Diabetic Mothers.
  264. Nephropathy, but not retinopathy, is associated with the development of heart disease in Type 1 diabetes: a 12-year observation study of 462 patients.
  265. Diabetic Retinopathy Is Associated With Mortality and Cardiovascular Disease Incidence.
  266. Simultaneous type 1 diabetes onset in mother and son coincident with an enteroviral infection.
  267. Achieving and maintaining insulin independence in human islet transplant recipients.
  268. Islet Transplantation Is Associated With an Improvement of Cardiovascular Function in Type 1 Diabetic Kidney Transplant Patients. Free full text available in HTML and PDF formats.
  269. The Beneficial Effects of Pancreas Transplant Alone on Diabetic Nephropathy.
  270. Natural History of Kidney Graft Survival, Hypertrophy, and Vascular Function in End-Stage Renal Disease Type 1 Diabetic Kidney-Transplanted Patients; Beneficial impact of pancreas and successful islet cotransplantation.
  271. NIH Researchers Discover How Insulin Allows Entry of Glucose Into Cells.

    22 May 2005

  272. Scientists clone cells from human patients. See also Stem cell breakthrough and Stem cell breakthrough in UK and South Korea.
  273. Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy. See also A Penn State College of Medicine study suggests that a common antibiotic called minocycline may slow or prevent diabetic retinopathy, a complication of diabetes that is the leading cause of blindness in people ages 20 to 74.
  274. Normalization of glucose post-transplantation of pig pancreatic anlagen into non-immunosuppressed diabetic rats depends on obtaining anlagen prior to embryonic day 35. See also Precise timing enabled pig-to-rat transplants to cure diabetes.
  275. Developments in the prediction of type 1 diabetes mellitus, with special reference to insulin autoantibodies.
  276. The incidence of visual impairment due to diabetic retinopathy in Leeds.
  277. Involvement of circulating endothelial progenitor cells and vasculogenic factors in the pathogenesis of diabetic retinopathy.
  278. Childhood and adolescent diabetes.
  279. Relationship between the incidence of type 1 diabetes and maternal enterovirus antibodies: time trends and geographical variation.
  280. Islet cell related antibodies and type 1 diabetes associated with echovirus 30 epidemic: A case report.
  281. Baculovirus p35 increases pancreatic beta-cell resistance to apoptosis.
  282. Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage.
  283. The sweet thing about Type 1 diabetes: A cryoprotective evolutionary adaptation. See also The New York Times article New Theory Places Origin of Diabetes in an Age of Icy Hardships.

    15 May 2005

  284. Insulin sparks autoimmunity. See summary at Study at UCDHSC Identifies Crucial Islet Target in Type 1 Diabetes; Finding Is Likely to Transform the Study of Diabetes Autoimmunity. See also CU team discovers crucial clue to diabetes; Health Sciences scientists find proof of trigger in Type 1.
  285. C-reactive protein concentration is not related to islet autoimmunity status in offspring of parents with type 1 diabetes.
  286. Can Continuous Glucose Monitoring Provide Objective Documentation Of Hypoglycemia Unawareness?
  287. Evaluation of metabolic control using a continuous subcutaneous glucose monitoring system in patients with type 1 diabetes mellitus who achieved insulin independence after islet cell transplantation.
  288. "Catastrophic" rise in child diabetes.
  289. Increasing incidence of type 1 diabetes in population from Santiago of Chile: trends in a period of 18 years (1986-2003). Free full text available in HTML format.
  290. Effect of the immunosuppressive regime of Edmonton protocol on the long-term in vitro insulin secretion from islets of two different species and age categories.
  291. LCT reports nine-year survival of transplanted pig islet cells in a diabetic patient. See also Nine-year survival of transplanted pig islet cells in a diabetic patient.
  292. Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope.
  293. Subcutaneous xenotransplantation of bovine pancreatic islets.
  294. Prevention and cure of autoimmune diabetes in nonobese diabetic mice by continuous administration of FTY720.
  295. Blood flow in the skin of type 1 diabetic patients before and after combined pancreas/kidney transplantation.
  296. Prolonged allogeneic islet graft survival by protoporphyrins.
  297. Intra- and Inter-islet Synchronization of Metabolically Driven Insulin Secretion.

    8 May 2005

  298. Pancreas donation for islet transplantation.
  299. Pancreas islet transplantation in patients with type 1 diabetes mellitus after kidney transplantation.
  300. Kidney-Pancreas Transplants: Is It So Difficult to Start a Program?
  301. Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population.
  302. Bone calcium changes during diabetic ketoacidosis: A comparison with lactic acidosis due to volume depletion.
  303. Impact of insulin on microvascular blood flow and endothelial cell function in the postprandial state in patients with Type 1 diabetes.
  304. Increased plasma adiponectin concentrations are associated with microangiopathy in type 1 diabetic subjects.
  305. Beneficial autoimmunity in Type 1 diabetes mellitus.

    1 May 2005

  306. Effects of Oral Insulin in Relatives of Patients With Type 1 Diabetes: The Diabetes Prevention Trial–Type 1 concluded that "...oral insulin did not delay or prevent type 1 diabetes."
  307. Study shows natural glucose byproduct may prevent brain damage and cognitive impairment after diabetic coma. See also Pyruvate Administered After Severe Hypoglycemia Reduces Neuronal Death and Cognitive Impairment.
  308. Time-Action Profile of Inhaled Insulin in Comparison With Subcutaneously Injected Insulin Lispro and Regular Human Insulin.
  309. Living-Donor Islet Transplantation: A Newsmaker Interview With Shinichi Matsumoto, MD, PhD.
  310. Incretin hormones and insulin sensitivity.
  311. Producing Insulin from Neural Cells. Also available in PDF format.
  312. Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells. Also available in PDF format. See also Stem cells from brain transformed to produce insulin at Stanford.
  313. The effect of perindopril on cardiovascular morbidity and mortality in patients with diabetes in the EUROPA study: results from the PERSUADE substudy.
  314. Seasonal patterns in monthly hemoglobin A1c values.
  315. Ovarian Function During Puberty In Girls With Type 1 Diabetes Mellitus (DM1): Response To Leuprolide. Free full text available in PDF format.
  316. Approaches for the cure of type 1 diabetes by cellular and gene therapy.
  317. Advanced Glycation End Products Are Associated With Pulse Pressure in Type 1 Diabetes. The EURODIAB Prospective Complications Study.
  318. Magnesium Deficiency Is Associated With Insulin Resistance in Obese Children.
  319. Rebuilding Blocks is about stem cell research.
  320. The role of vitamin D in protecting type 1 diabetes mellitus. Free full text available in HTML format.
  321. Changes in Intestinal Morphology and Permeability in the BioBreeding Rat Before the Onset of Type 1 Diabetes.

    24 April 2005

  322. Dietary manipulation of beta cell autoimmunity in infants at increased risk of type 1 diabetes: a pilot study.
  323. Insights into the acute cerebral metabolic changes associated with childhood diabetes.
  324. Differentiation of Insulin-Producing Cells from Human Neural Progenitor Cells.
  325. Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity.
  326. Psychosocial aspects of xenotransplantation: survey in adolescent recipients of porcine islet cells.
  327. Type 1 Diabetes in the Spanish Population: additional factors to Class II HLA-DR3 and -DR4. Free full text available in HTML and PDF formats.
  328. Structural-tridimensional study of yolk sac in pregnancies complicated by diabetes.
  329. NOVA offers stories and information about Stem Cells. The video segment focuses on Lauren Stanford, a teenager with type 1 diabetes, and Doug Melton from Harvard, a stem cell researcher who has two children with type 1 diabetes.

    17 April 2005

  330. Vitamin D-binding protein gene polymorphism association with IA-2 autoantibodies in type 1 diabetes.
  331. The Spring 2005 issue of Diabetes Update from Diabetes UK explores work being done to find a vaccine to prevent type 1 diabetes. See also Vaccine gives hope to Type 1 diabetics.
  332. Diabetes-related antibodies in euglycemic subjects.
  333. Should We Be Performing Pancreas Transplants?
  334. Widening of foot processes in normoalbuminuric adolescents with type 1 diabetes.
  335. Researcher grows new insulin-secreting beta cells from pancreatic tissue.
  336. Scientists use transcription factors to increase insulin production in diabetic mice.
  337. Scientists at diabetes center find genetic defects in immunological tolerance.
  338. The Boston Globe has an online section devoted to the stem cell research debate.

    10 April 2005

  339. Early infant diet and risk of type 1 diabetes mellitus in Belgrade children.
  340. Do microbes have a causal role in type 1 diabetes? is the free, full text article to a paper previously cited here.
  341. Clinical characteristics at onset of Type 1 diabetes in children diagnosed between 1977 and 2001 in the south-east region of Sweden.
  342. Clinical implications of N-(carboxymethyl)lysine, advanced glycation end product, in children and adolescents with type 1 diabetes.
  343. Human blood cells coaxed to produce insulin.
  344. Reluctance of French patients with type 1 diabetes to undergo pig pancreatic islet xenotransplantation.
  345. Transplantation of neonatal porcine islets and sertoli cells into nonimmunosuppressed nonhuman primates.
  346. Xenotransplantation of neonatal porcine islets and Sertoli cells into nonimmunosuppressed streptozotocin-induced diabetic rats.
  347. Protection of islets in culture by delivery of oxygen binding neuroglobin via protein transduction.
  348. Impairment in orthostatic tolerance during heat exposure in individuals with Type I and Type II Diabetes.

    3 April 2005

  349. The role of the innate immunity in islet transplantation.
  350. Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans.
  351. Regulatory T cells and type 1 diabetes.
  352. Predicting type 1 diabetes.
  353. Glycaemic effects of incretins in Type 1 diabetes mellitus A concise review, with emphasis on studies in humans.
  354. Human blood cells coaxed to produce insulin.
  355. Xenogenous transplantation of insular cells without immunosuppressive therapy in the treatment of insulin-dependent diabetes.
  356. TRIGR - Trial to Reduce the Incidence of type 1 diabetes in the Genetically at Risk.
  357. Clinical outcomes of phacoemulsification cataract surgery in diabetes patients: visual function (VF-14), visual acuity and patient satisfaction.
  358. Changes in Glucose Tolerance Over Time in Women with Polycystic Ovary Syndrome: A Controlled Study. Free full text available in PDF format.
  359. Intrauterine exposure to diabetes is a determinant of hemoglobin A1c and systolic blood pressure in Pima Indian children. Free full text available in PDF format.
  360. High-sensitivity C-reactive protein is associated with insulin resistance and cardiovascular autonomic dysfunction in type 2 diabetic patients.

    27 March 2005

  361. Change in perceived health and functioning over time in patients with type I diabetes mellitus.
  362. The stages of type 1A diabetes: 2005.
  363. Maternal Efforts to Prevent Type 1 Diabetes in At-Risk Children.
  364. Autoantibody "Subspecificity" in Type 1 Diabetes: Risk for organ-specific autoimmunity clusters in distinct groups.
  365. Residual insulin secretion at diagnosis of type 1 diabetes is independently associated with both, age of onset and HLA genotype.
  366. Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset.
  367. Critical Role Macrophage Migration Inhibitory Factor (MIF) Activity in Experimental Autoimmune Diabetes. Free full text available in PDF format.
  368. Coronary Artery Disease Is Common in Nonuremic, Asymptomatic Type 1 Diabetic Islet Transplant Candidates.
  369. Pancreas transplantation in Ireland.
  370. Depression-related hyperglycemia in type 1 diabetes: a mediational approach.
  371. Depressive Symptoms and Mortality among Persons with and without Diabetes.
  372. Development of a New Fear of Hypoglycemia Scale: Preliminary Results.
  373. Parent and Adolescent Versions of the Diabetes-Specific Parental Support for Adolescents' Autonomy Scale: Development and Initial Testing.
  374. Cardiovascular disease morbidity and mortality in patients with type 1 diabetes mellitus : management strategies.
  375. Inhalation of Insulin (Exubera) Is Associated With Augmented Disposal of Portally Infused Glucose in Dogs.
  376. Effects of Glycemic Control on Target Organ Responses to Epinephrine in Type 1 Diabetes.
  377. Increased renal glucose metabolism in Type 1 diabetes mellitus.
  378. Early referral to kidney-pancreas transplantation in type 1 diabetics prevents ESRD.
  379. Acute Induction of Gene Expression in Brain and Liver by Insulin-Induced Hypoglycemia.
  380. Prevalence of type 1 diabetes among 6- to 18-year-old Kuwaiti children.
  381. Achieving Permanent Survival of Islet Xenografts by Independent Manipulation of Direct and Indirect T-Cell Responses.
  382. Reversal of Diabetes in Pancreatectomized Pigs After Transplantation of Neonatal Porcine Islets.
  383. Latent autoimmune diabetes of adulthood. Unique features that distinguish it from types 1 and 2.
  384. The Metabolic Syndrome and Concentrations of C-Reactive Protein Among U.S. Youth.
  385. Diabesity : are weight loss medications effective?
  386. The prevalence of obesity and associated morbidity among 17-year-old Israeli conscripts.
  387. Combined oral contraceptives in the treatment of polycystic ovary syndrome.

    20 March 2005

  388. Younger age at diagnosis of type 1 diabetes mellitus in children of immigrated families born in Italy.
  389. Combination Therapy with Epidermal Growth Factor and Gastrin Induces Neogenesis of Human Islet {beta}-Cells from Pancreatic Duct Cells and an Increase in Functional {beta}-Cell Mass.
  390. Inhibition of cellular immune responses to encapsulated porcine islet xenografts by simultaneous blockade of two different costimulatory pathways.
  391. Effects of diet and exercise on muscle and liver intracellular lipid contents and insulin sensitivity in type 2 diabetic patients.
  392. Cancer Drug for Diabetes? summarizes Imatinib and Regression of Type 2 Diabetes.
  393. Chemists Identify Key Gene in Development of Type 1 Diabetes.

    13 March 2005

  394. Do microbes have a causal role in type 1 diabetes?
  395. Immune modulation for prevention of type 1 diabetes mellitus.
  396. Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes.
  397. Mean HbA(1)c over 18 years predicts carotid intima media thickness in women with type 1 diabetes.
  398. Impaired microvascular function related to poor metabolic control in young patients with diabetes.

    6 March 2005

  399. Antibody Response to Inhaled Insulin in Patients with Type 1 or Type 2 Diabetes.
  400. Modeling insulin action for development of a closed-loop artificial pancreas.
  401. Run-to-Run Control of Meal-Related Insulin Dosing.
  402. Impaired Retinal Angiogenesis in Diabetes: Role of Advanced Glycation End Products and Galectin-3.
  403. Increased aortic stiffness is persistent in type 1 diabetic women: a follow-up study.
  404. Sex differences in the effect of diabetes duration on coronary heart disease mortality.
  405. Anemia with impaired erythropoietin response in diabetic patients.
  406. Lung function and glucose metabolism: an analysis of data from the third national health and nutrition examination survey.
  407. Bungled insulin production may be a culprit in diabetes, University of Michigan researchers say. See Proinsulin disulfide maturation and misfolding in the endoplasmic reticulum.
  408. Toxin-based selection of insulin-producing cells with improved defense properties for islet cell transplantation.
  409. Retrovirus-Like Long-Terminal Repeat DQ-LTR13 and Genetic Susceptibility to Type 1 Diabetes and Autoimmune Addison’s Disease. Free full text available in HTML and PDF formats.

    27 February 2005

  410. Long-Term Graft Function of Adult Rat and Human Islets Encapsulated in Novel Alginate-Based Microcapsules After Transplantation in Immunocompetent Diabetic Mice.
  411. Effects of Sustained Insulin-Induced Hypoglycemia on Cardiovascular Autonomic Regulation in Type 1 Diabetes.
  412. Effects of Pramlintide on Postprandial Glucose Excursions and Measures of Oxidative Stress in Patients With Type 1 Diabetes.
  413. Fructose Normalizes Specific Counterregulatory Responses to Hypoglycemia in Patients With Type 1 Diabetes.
  414. Reduced plasma total homocysteine concentrations in Type 1 diabetes mellitus is determined by increased renal clearance.
  415. Experimental Diabetic Neuropathy With Spontaneous Recovery: Is There Irreparable Damage?
  416. Associations of Mortality and Diabetes Complications in Patients With Type 1 and Type 2 Diabetes.
  417. The annual incidence of diabetic complications in a population of patients with Type 1 and Type 2 diabetes.
  418. Reduced Prevalence of Limited Joint Mobility in Type 1 Diabetes in a U.K. Clinic Population Over a 20-Year Period.
  419. Has Control of Hypercholesterolemia and Hypertension in Type 1 Diabetes Improved Over Time?
  420. Youth Type 2 Diabetes: Insulin resistance, ß-cell failure, or both?

    20 February 2005

  421. Single-Donor, Marginal-Dose Islet Transplantation in Patients With Type 1. See also U of M reports advance in diabetes treatment and Single-Donor Pancreas Islet Transplantation Procedure Shows Promise.
  422. Caries risk assessment as a predictor of metabolic control in young Type 1 diabetics.
  423. The annual incidence of diabetic complications in a population of patients with Type 1 and Type 2 diabetes.
  424. The electrophysiological findings of subclinical neuropathy in patients with recently diagnosed type 1 diabetes mellitus.
  425. Vasoactive mediators and retinopathy during type 1 diabetic pregnancy.
  426. Screening for associated autoimmunity in type 1 diabetes mellitus with respect to diabetes control. Free full text available in PDF format.
  427. Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) Collection: the PTPN22 620W Allele Associates with Multiple Autoimmune Phenotypes.

    13 February 2005

  428. Science - Charitable Choices by Neil Munro offers an assessment of the issues associated with funding research proposed by Dr. Denise Faustman and supported by the Iacocca Foundation.
  429. Use of Anti-CD3 Monoclonal Antibody to Induce Immune Regulation in Type 1 Diabetes.
  430. Unravelling the pathogenesis of type 1 diabetes with proteomics-present and future directions. Free full text available in PDF format.
  431. Alba Therapeutics Corporation Reports the Successful Treatment of Type I Diabetes in the BB/wor Rat Model of Diabetes with Zonulin Antagonist AT-1001. See also Baltimore Biotech Gains in Diabetes Fight and Alba Therapeutics.
  432. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus.
  433. Prevalence of diabetes-associated autoantibodies in schoolchildren: the Karlsburg type 1 diabetes risk study.
  434. Incidence and clinical manifestations at onset of type 1 diabetes mellitus in Galicia (Spain): 2001-2002.
  435. Elevated Lymphocyte Expression of CLIP Is Associated with Type 1 Diabetes and May Be a Useful Marker of Autoimmune Susceptibility.
  436. Experimental autoimmune diabetes: a new tool to study mechanisms and consequences of insulin-specific autoimmunity.
  437. Use of the Internet to search for information in type 1 diabetes children and adolescents: A cross-sectional study.
  438. Islet cell response in the neonatal rat after exposure to a high fat diet during pregnancy.

    6 February 2005

  439. Living donor diabetes transplant. See also World-First Living Donor Transplant of Islet Cells a Success and Shot in the arm! Breakthrough transplant gives diabetics hope.
  440. Is Transplantation in Diabetics Justified?
  441. Successful islet after kidney transplantations in a distance over 1000 kilometres: Preliminary results of the Budapest-Geneva collaboration.
  442. Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes.
  443. Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes-the EURODIAB Prospective Complications Study.
  444. Social and psychological characteristics of Kuwaiti children and adolescents with type 1 diabetes.
  445. Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in Chilean subjects: a case-parent study.
  446. Diminished Th1-like response to autoantigens in children with a high risk of developing type 1 diabetes.

    30 January 2005

  447. Psychological Stress May Induce Diabetes-Related Autoimmunity in Infancy.
  448. Parental age at delivery, birth order, birth weight and gestational age are associated with the risk of childhood Type 1 diabetes: a UK regional retrospective cohort study.
  449. Increasing body weight predicts the earlier onset of insulin-dependant diabetes in childhood: testing the 'accelerator hypothesis' (2).
  450. Vitamin d in type 1 diabetes prevention.
  451. Psychiatric morbidity and health outcome in Type 1 diabetes - perspectives from a prospective longitudinal study.
  452. Insulin treatment and cardiovascular disease; friend or foe? A point of view.
  453. Vascular risk factors and diabetic neuropathy.
  454. Predicting vascular risk in Type 1 diabetes: stratification in a hospital based population in Scotland.
  455. The Relationship of Diabetic Retinopathy to Preclinical Diabetic Glomerulopathy Lesions in Type 1 Diabetic Patients: The Renin-Angiotensin System Study.
  456. Unchanged incidence of diabetic nephropathy in Type 1 diabetes: a nation-wide study in Iceland.
  457. Cumulative Incidence of Type 1 Diabetes in 10,168 Siblings of Finnish Young-Onset Type 1 Diabetic Patients.
  458. Secondary Attack Rate of Type 1 Diabetes in Colorado Families.
  459. Residual beta-Cell Function and Male/Female Ratio Are Higher in Incident Young Adults Than in Children.
  460. Pancreatic Islet Transplantation.
  461. Antigen-Specific FoxP3-Transduced T-Cells Can Control Established Type 1 Diabetes. Free full text available in HTML and PDF formats.
  462. 'Disappearing diabetes'-resolution of apparent Type 1 diabetes in a patient with AIDS and cytomegalovirus (CMV) infection.
  463. Fast-food habits, weight gain, and insulin resistance (the CARDIA study): 15-year prospective analysis. See also 15-year Study Shows Strong Link Between Fast Food, Obesity And Insulin Resistance.
  464. Dynamic Changes in beta-Cell Mass and Pancreatic Insulin During the Evolution of Nutrition-Dependent Diabetes in Psammomys obesus. Full text available in HTML format.

    23 January 2005

  465. Spleen may be source of versatile stem cells. See also Adult Spleen Cells Demonstrate Regenerative Properties Associated with Embryonic Stem Cells.
  466. Stem cell treatment reverses diabetes: Argentine researchers.
  467. Insulin autoantibodies in cord blood from neonates with and without a sibling with type 1 diabetes-prevalence and characterization.
  468. Sudden cardiac death in diabetes mellitus: risk factors in the Rochester diabetic neuropathy study.
  469. Antioxidative treatment prevents activation of death-receptor- and mitochondrion-dependent apoptosis in the hearts of diabetic rats.
  470. Relationship between HbA(1)c and mortality in a Japanese population.
  471. Coffee consumption and glucose tolerance status in middle-aged Japanese men.
  472. Coffee consumption and incidence of impaired fasting glucose, impaired glucose tolerance, and type 2 diabetes: the Hoorn Study.
  473. Diagnosis and management of maturity-onset diabetes of the young.
  474. Chorea and Broca aphasia induced by diabetic ketoacidosis in a type 1 diabetic patient diagnosed as Moyamoya disease.

    16 January 2005

  475. Pubertal changes in serum leptin levels in adolescents with type 1 diabetes mellitus: a controlled longitudinal study.
  476. Comparison of Pharmacokinetic and Pharmacodynamic Properties of Single-Dose Oral Insulin Spray and Subcutaneous Insulin Injection in Healthy Subjects Using the Euglycemic Clamp Technique.
  477. Raised glucose concentrations and diabetes are associated with cancer risk. Also available in PDF format.
  478. Ten-year incidence of self-reported erectile dysfunction in people with long-term type 1 diabetes.
  479. Impact of simultaneous kidney-pancreas transplant and timing of transplant on kidney allograft survival.
  480. The Family Investigation of Nephropathy and Diabetes (FIND); Design and methods.
  481. Apolipoprotein C-III protein concentrations and gene polymorphisms in Type 1 diabetes; Associations with microvascular disease complications in the DCCT/EDIC cohort.
  482. Osteoporosis and diabetes.
  483. Metabolic Risk During Antipsychotic Treatment.
  484. Obesity and type 2 diabetes mellitus: a population-based study of adolescents.

    9 January 2005

  485. Regeneration of the pancreatic beta cell. Free full text available in HTML and PDF formats.
  486. Rescue purification maximizes the use of human islet preparations for transplantation.
  487. Endothelial Function Evaluated by Flow-Mediated Dilatation in Pediatric Vascular Disease.
  488. C-Reactive Protein Levels and Outcomes after Statin Therapy.
  489. A new challenge in pediatric obesity: Pediatric hyperglycemic hyperosmolar syndrome.

    2 January 2005

  490. The relationship of glucose tolerance to sleep disorders and daytime sleepiness.
  491. Risk factors for cardiac autonomic neuropathy in type 1 diabetes mellitus.
  492. Prevention of type 1 diabetes: from the view point of beta cell damage.
  493. Alterations of the female reproductive system in recipients of islet grafts.
  494. Recent advance in hepatic insulin gene therapy.
  495. Generation of new islets from stem cells.
  496. Lisofylline: a potential lead for the treatment of diabetes.
  497. Diabetes Acceleration or Prevention by a Coxsackievirus B4 Infection: Critical Requirements for both Interleukin-4 and Gamma Interferon.
  498. High frequency of abnormal glucose tolerance in DQA1*0102/DQB1*0602 relatives identified as part of the Diabetes Prevention Trial-Type 1 Diabetes.
  499. The TGF-beta1 gene codon 10 polymorphism contributes to the genetic predisposition to nephropathy in Type 1 diabetes.

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