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Research News From 2007

    30 December 2007

  1. No change in apolipoprotein AI metabolism when subcutaneous insulin infusion is replaced by intraperitoneal insulin infusion in type 1 diabetic patients.
  2. Insulin Mutation Screening in 1044 Patients with Diabetes: Mutations in the INS gene are a Common Cause of Neonatal Diabetes but a Rare Cause of Diabetes Diagnosed in Childhood or Adulthood.
  3. Family-based analysis of vitamin D receptor gene polymorphisms and type 1 diabetes in the population of South Croatia.
  4. Plasma concentration of asymmetric dimethylarginine (ADMA) predicts cardiovascular morbidity and mortality in type 1 diabetic patients with diabetic nephropathy.
  5. Effects of pyridoxamine in combined phase 2 studies of patients with type 1 and type 2 diabetes and overt nephropathy.
  6. The effects of type 1 diabetes on cerebral white matter.

    23 December 2007

  7. Effects of controlled hypoglycaemia on cardiac repolarisation in patients with type 1 diabetes.
  8. "Type 1 on type 2" diabetes mellitus: autoimmune type 1 diabetes superimposed on established type 2 diabetes. Free full text available in PDF format.
  9. Proinsulin C-peptide abrogates type-1 diabetes-induced increase of renal endothelial nitric oxide synthase in rats.
  10. Prevalence and determinants of elevated apolipoprotein B and dense LDL in youths with type 1 and type 2 diabetes. Free full text available in PDF format.
  11. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study.
  12. A genome-wide scan for type 1 diabetes susceptibility genes in nuclear families with multiple affected siblings in Finland. Free full text available in PDF format.
  13. Neonatal Formula Feeding Leads to Immunological Alterations in an Animal Model of Type 1 Diabetes.

    16 December 2007

  14. The Long Road to Beta Cells -- Quest for type 1 diabetes cure inches forward.
  15. Knock Out, Knock In, Knock Down — Genetically Manipulated Mice and the Nobel Prize (PDF version) summarizes the process of removing and inserting genes into an animal's DNA, which is used extensively in research, including diabetes-related research.
  16. Humoral immune responses of Type-1 Diabetes patients to M. avium subspecies paratuberculosis lend support to the infectious trigger hypothesis.
  17. Regulated beta-cell regeneration in the adult mouse pancreas.
  18. Treatment of type 1 diabetes by transplantation of bone-derived mesenchymal stem cells expressing human insulin gene: experiment with mice.
  19. Defining pancreatic endocrine precursors and their descendants.
  20. Proinsulin C-peptide Constricts Glomerular Afferent Arterioles in Diabetic Mice. A Potential Reno-Protective Mechanism.
  21. The therapeutic potential of VEGF inhibition in diabetic microvascular complications.
  22. The G53D Mutation in Kir6.2 (KCNJ11) is Associated with Neonatal Diabetes and Motor Dysfunction in Adulthood that is Improved with Sulfonylurea Therapy. Free full text available in PDF format.

    9 December 2007

  23. Proinsulin C-peptide -- the bioactive peptide with a huge promise.
  24. A Risk Score for Type 1 Diabetes Derived from Autoantibody Positive Participants in The Diabetes Prevention Trial- Type 1.
  25. Familiality of diabetes mellitus.
  26. The occurrence and analysis of chosen risk factors of DKA among children with new onset of DMT1.
  27. Double or hybrid diabetes associated with an increase in type 1 and type 2 diabetes in children and youths.
  28. Epidemiology of childhood type 2 diabetes and obesity.
  29. Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice. Free full text available in HTML and PDF formats.
  30. B cell depletion: a novel therapy for autoimmune diabetes? Free full text available in HTML and PDF formats.
  31. Incidence and trends of childhood Type 1 diabetes in Croatia from 1995 to 2003.
  32. hsCRP protein in children and adolescents with diabetes type 1.
  33. Proteomics and diabetic nephropathy.
  34. Induction of immune tolerance to facilitate beta cell regeneration in type 1 diabetes.
  35. Reduced Immunogenicety of First Trimester Human Fetal Pancreas.
  36. Analysis of SNPs Identifies Major Type 1A Diabetes Locus Telomeric of the MHC.

    2 December 2007

  37. Increasing GLP-1-induced ß-cell Proliferation By Silencing The Negative Regulators Of Signaling CREM And DUSP14.
  38. Murine Anti-Thymocyte Globulin Therapy Alters Disease Progression in NOD Mice by a Time Dependent Induction of Immunoregulation.
  39. Novel human protein networks of genetic interactions in type 1 diabetes.
  40. The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes. Free full text available in PDF format.
  41. Parental country of birth is a major determinant of childhood type 1 diabetes in Sweden.
  42. Seasonality of month of birth differs between type 1 diabetes patients with pronounced beta-cell autoimmunity and individuals with lesser or no beta-cell autoimmunity.
  43. Relationship of highly sensitive C-reactive protein and lipid levels in adolescents with type 1 diabetes mellitus.
  44. Oxidative Stress and the JNK Pathway are Involved in the Development of Type 1 and Type 2 Diabetes.
  45. Skin Autofluorescence: A Tool to Identify Type 2 Diabetic Patients at Risk for Developing Microvascular Complications.
  46. Proteinuria disappears promptly after simultaneous kidney-pancreas transplantation in nephrotic diabetic patients with near-normal GFR.
  47. RAGE and Experimental Diabetic Neuropathy.

    25 November 2007

  48. Family history of diabetes, autoimmunity, and risk factors for cardiovascular disease among children with diabetes in the SEARCH for Diabetes in Youth Study.
  49. The islet autoantibody titres: their clinical relevance in latent autoimmune diabetes in adults (LADA) and the classification of diabetes mellitus.
  50. Increased TLR2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Pro-inflammatory state. Free full text available in PDF format.
  51. Essential roles of TGF-{beta} in anti-CD3 antibody therapy: reversal of diabetes in nonobese diabetic mice independent of Foxp3+CD4+ regulatory T cells. Free full text available in PDF format.

    18 November 2007

  52. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A.
  53. Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.
  54. Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes.
  55. A Risk Score for Type 1 Diabetes Derived from Autoantibody Positive Participants in The Diabetes Prevention Trial- Type 1.
  56. Uncomplicated type 1 diabetes and preclinical left ventricular myocardial dysfunction: Insights from echocardiography and exercise cardiac performance evaluation.
  57. Progression of coronary artery calcium in type 1 diabetes mellitus.
  58. An Insulin Infusion Advisory System for Type 1 Diabetes Patients based on Non-Linear Model Predictive Control Methods.
  59. Detection of Hypoglycemic Episodes in Children with Type 1 Diabetes using an Optimal Bayesian Neural Network Algorithm.
  60. Prediction of glucose excursions under uncertain parameters and food intake in intensive insulin therapy for type 1 diabetes mellitus.
  61. A Communication and Information Technology Infrastructure for Real Time Monitoring and Management of Type 1 Diabetes Patients.
  62. Attenuation of Counterregulatory Responses to Recurrent Hypoglycemia by Active Thalamic Inhibition: A Mechanism for Hypoglycemia-Associated Autonomic Failure.
  63. High Prevalence of Type 2 Diabetes and Pre-Diabetes in Adult Offspring of Women with Gestational Diabetes Mellitus or Type 1 Diabetes – The Role of Intrauterine Hyperglycemia.
  64. Impaired glucose balance and subtypes of diabetes mellitus revealed in intravenous glucose tolerance test.
  65. Potential risk of porcine endogenous retrovirus cross-species transmission in neonatal pig islets under xenotransplanted condition.

    11 November 2007

  66. Glucagon-like-peptide-1 inhibits blood-brain glucose transfer in humans.
  67. Prevalence of vitamin D receptor gene polymorphism in a Uruguayan population and its relation to type 1 diabetes mellitus.
  68. Pro-inflammatory Variants of DRB1 and RAGE Genes Are Associated with Susceptibility to Pediatric Type 1 Diabetes: A New Hypothesis on the Adaptive Role of Autoimmunity.
  69. Distribution of neuropeptide Y Leu7Pro polymorphism in patients with type 1 diabetes and diabetic nephropathy among Swedish and American populations.
  70. Comparative therapeutic effects of orally administered 1,25-dihydroxyvitamin D(3) and 1alpha-hydroxyvitamin D(3) on type-1 diabetes in non-obese diabetic mice fed a normal-calcaemic diet.
  71. Pancreatic Islet Cell Transplant for Treatment of Diabetes.
  72. Pancreas-Kidney and Pancreas Transplantation for the Treatment of Diabetes Mellitus.
  73. Induction of Robust Diabetes Resistance and Prevention of Recurrent Type 1 Diabetes Following Islet Transplantation by Gene Therapy.
  74. Epitope Analysis of GAD65 Binding in both Cord Blood and at the Time of Clinical Diagnosis of Childhood Type 1 Diabetes.
  75. The role of virus infections in the pathogenesis of type 1 diabetes--a case report.

    4 November 2007

  76. Early infant feeding and risk of type 1 diabetes mellitus-a nationwide population-based case-control study in pre-school children.
  77. Low-risk HLA genotype in Type 1 diabetes is associated with less destruction of pancreatic B-cells 12 months after diagnosis.
  78. Occurrence of enterovirus RNA in serum of children with newly diagnosed type 1 diabetes and islet cell autoantibody-positive subjects in a population with a low incidence of type 1 diabetes.
  79. Islet cell autoantibodies in African patients with Type 1 and Type 2 diabetes in Dar es Salaam Tanzania: a cross sectional study. Free full text available in PDF format.
  80. Stem cell genes may provide medicine's dream ticket includes a discussion of the work of enGene, Inc., which is working on a genetic engineering cure for type 1 diabetes.
  81. Hematopoietic Mixed Chimerism Derived From Allogeneic Embryonic Stem Cells Prevents Autoimmune Diabetes Mellitus In Nod Mice.
  82. Immune modulation induced by tuberculosis DNA vaccine protects non-obese diabetic mice from diabetes progression.
  83. Allogeneic islet transplantation.
  84. Partial Pancreatectomy In Adult Humans Does Not Provoke Beta Cell Regeneration.
  85. Simultaneous islet-kidney vs pancreas-kidney transplantation in type 1 diabetes mellitus: a 5 year single centre follow-up.
  86. Cardiovascular impairment in children, adolescents, and young adults with type 1 diabetes mellitus (T1DM).
  87. Burning mouth syndrome and peripheral neuropathy in patients with type 1 diabetes mellitus.
  88. Increased serum pigment epithelium-derived factor is associated with microvascular complications, vascular stiffness and inflammation in Type 1 diabetes.
  89. Understanding the pathology and mechanisms of type I diabetic bone loss.
  90. Detection of a Meal Using Continuous Glucose Monitoring (CGM): Implications for an Artificial ß-cell.
  91. Inflammatory cytokines in insulin-treated patients with type 2 diabetes.
  92. Menin Controls Growth of Pancreatic ß-Cells in Pregnant Mice and Promotes Gestational Diabetes Mellitus.
  93. Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart.

    28 October 2007

  94. Immune intervention at diagnosis--should we treat children to preserve beta-cell function?
  95. Metabolic aspects of pig-to-monkey (Macaca fascicularis) islet transplantation: implications for translation into clinical practice.
  96. Putative Delays in Interstitial Fluid (ISF) Glucose Kinetics Can Be Attributed to the Glucose Sensing Systems Used to Measure Them Rather Than the Delay in ISF Glucose Itself.
  97. Worldwide childhood type 1 diabetes incidence--what can we learn from epidemiology?
  98. Differential diagnosis of type 1 diabetes: which genetic syndromes need to be considered?
  99. Identifying children at particular risk of long-term diabetes complications.
  100. Sequence of progression of albuminuria and decreased GFR in persons with type 1 diabetes: a cohort study.
  101. Doppler ultrasonography imaging of hemodynamic alteration of retrobulbar circulation in type 1 diabetic children and adolescents without retinopathy.
  102. Captopril Inhibits Capillary Degeneration in the Early Stages of Diabetic Retinopathy.
  103. Insulin Resistance And Progression To Type 1 Diabetes In The European Nicotinamide Diabetes Intervention Trial (ENDIT).
  104. Insulin administration may trigger pancreatic beta-cell destruction in patients with type 2 diabetes.
  105. Role of Low Energy Expenditure and Sitting in Obesity, Metabolic Syndrome, Type 2 Diabetes, and Cardiovascular Disease.

    21 October 2007

  106. Type 1 diabetes intervention trials 2007: where are we and where are we going?
  107. Pancreas and islet cell transplantation in diabetes.
  108. Long-term engraftment following transplantation of pig pancreatic primordia into non-immunosuppressed diabetic rhesus macaques. See also Cross-species transplant in rhesus macaques is step toward diabetes cure for humans.
  109. Induction of insulin secretion in engineered liver cells by nitric oxide. Free full text available in PDF format.
  110. Recent enterovirus infection in type 1 diabetes: Evidence with a novel IgM method.
  111. The effect of birth order and parental age on the risk of type 1 and 2 diabetes among young adults.
  112. Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes.
  113. Protein restriction for diabetic renal disease.
  114. Robust Parameter Estimation in a Model for Glucose Kinetics in Type 1 Diabetes Subjects.

    14 October 2007

  115. Differential anti-diabetic efficacy of incretin agonists vs. DPP-4 inhibition in high fat fed mice.
  116. Beta-cell replacement in immunosuppressed recipients: old and new clinical indications.
  117. Functional waning of naturally-occurring CD4+ regulatory T cells contributes to the onset of autoimmune diabetes.
  118. Pluripotency Redux — Advances in Stem-Cell Research. See also Interview with Douglas Melton on the promise and limitations of recent advances in stem-cell research.
  119. Highly poly(ethylene) glycolylated islets improve long-term islet allograft survival without immunosuppressive medication.
  120. Inhaled insulin using AERx insulin Diabetes Management System (AERx iDMS).
  121. Hyperplastic islets observed in "reversed" NOD mice treated without hematopoietic cells.
  122. Mesenchymal Stem Cells Cooperate with Bone Marrow Cells in Therapy of Diabetes.
  123. Novel Effectors of Directed and ngn3 Mediated Differentiation of Mouse Embryonic Stem Cells into Endocrine Pancreas Progenitors.
  124. Encapsulation of porcine islets permits extended culture time and insulin independence in spontaneously diabetic BB rats.

    7 October 2007

  125. Inhibition of PKCepsilon Improves Glucose-Stimulated Insulin Secretion and Reduces Insulin Clearance. See also Proinsulin maturation, misfolding, and proteotoxicity and Sabotage in the insulin factory? Botched production of insulin molecule may kill pancreas cells and lead to diabetes, U-M study finds.
  126. Solving a critical part of the insulin puzzle. See also Aussie scientists make diabetes breakthrough.
  127. SIRT1 Improves Insulin Sensitivity under Insulin-Resistant Conditions by Repressing PTP1B. Free full text available in HTML and PDF formats.
  128. Fatty Acids And Insulin Modulate Myocardial Substrate Metabolism In Humans With Type 1 Diabetes Mellitus.
  129. Multiple SOD1/SFRS15 variants are associated with the development and progression of diabetic nephropathy: The DCCT/EDIC Genetics study.
  130. Cardiovascular disease risk prediction in type 1 diabetes: Accounting for the differences.
  131. Pancreatic scintigraphy with 99mTc-interleukin-2 at diagnosis of type 1 diabetes and after 1 year of nicotinamide therapy.
  132. No increased incidence of diabetes in antidepressant users.

    30 September 2007

  133. Omega-3 Polyunsaturated Fatty Acid Intake and Islet Autoimmunity in Children at Increased Risk for Type 1 Diabetes. See also Omega-3s may protect children from diabetes and Omega-3s fight diabetes.
  134. Early mortality in EURODIAB population-based cohorts of type 1 diabetes diagnosed in childhood since 1989. Free full text available in HTML and PDF formats.
  135. Glycaemic control and antibody status among patients with newly diagnosed Type 1 diabetes.
  136. Elevated serum levels of adiponectin in children, adolescents and young adults with type 1 diabetes and the impact of age, gender, body mass index and metabolic control: a longitudinal study.
  137. Environmental causes of type 1 diabetes.
  138. Presence of residual beta cells and co-existing islet autoimmunity in the NOD mouse during longstanding diabetes: a combined histochemical and immunohistochemical study.
  139. New sources of pancreatic beta cells.
  140. Revascularization and remodelling of pancreatic islets grafted under the kidney capsule.
  141. Rapid loss of intraportally transplanted islets: an overview of pathophysiology and preventive strategies.
  142. Homocysteine and diabetic retinopathy.

    23 September 2007

  143. Prediction of the clinical remission using the C-peptide level in type 1 diabetes in children.
  144. Familial Risk Factors for Microvascular Complications And Differential Male-Female Risk in a Large Cohort of American Families with Type 1 Diabetes. Free full text available in PDF format.
  145. Defective function of the Fas apoptotic pathway in type 1 diabetes mellitus correlates with age at onset.
  146. Quality of life after islet transplant: impact of the number of islet infusions and metabolic outcome.
  147. Development and preclinical assessment of a bioartificial pancreas.
  148. Animal models of spontaneous autoimmune disease: type 1 diabetes in the nonobese diabetic mouse.
  149. Arterial hypertension exacerbates oxidative stress in early diabetic retinopathy.

    16 September 2007

  150. Beta Cell transplantation and immunosuppression: can't live with it, can't live without it.
  151. Early Nutrition and Risk of Type 1 Diabetes Mellitus - A Nationwide Case-control Study in Preschool Children.
  152. The Environmental Determinants of Diabetes in the Young (TEDDY) study: study design.
  153. Impairment of skin capillary recruitment precedes chronic complications in patients with type 1 diabetes.
  154. Increased Expression of Monocyte CD11b (Mac-1) in Overweight Recent-Onset Type 1 Diabetic Children.
  155. Human islets derived from donors after cardiac death are fully biofunctional.
  156. Engraftment of adult porcine islet xenografts in diabetic nonhuman primates through targeting of costimulation pathways.
  157. Beta-cell replacement and regeneration: Strategies of cell-based therapy for type 1 diabetes mellitus.

    9 September 2007

  158. Recovery from diabetes in mice by ß cell regeneration. Free full text available in HTML and PDF formats.
  159. Prediction of type 1 diabetes among siblings of affected children and in the general population.
  160. Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis.
  161. Circulating CD4+CD25 high regulatory T cells and natural killer T cells in children with newly diagnosed type 1 diabetes or with diabetes-associated autoantibodies.
  162. CD40 is required for development of islet inflammation in the RIP-CD154 transgenic mouse model of type 1 diabetes.
  163. Evidence of Increased Inflammation and Microcirculatory Abnormalities in Patients with Type 1 Diabetes and Their Role in Microvascular Complications.
  164. The Role of Low Energy Expenditure and Sitting on Obesity, Metabolic Syndrome, Type 2 Diabetes, and Cardiovascular Disease.
  165. Association Between Low-Grade Systemic Inflammation and Type 2 Diabetes Mellitus Among Men and Women from the ATTICA Study.

    2 September 2007

  166. HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population.
  167. Expression of cholera toxin B–proinsulin fusion protein in lettuce and tobacco chloroplasts – oral administration protects against development of insulitis in non-obese diabetic mice. See also Insulin Grown in Plants Relieves Diabetes in Mice; UCF Study Holds Promise for Humans and Local Professor Begins Human Trials For Diabetes Cure.
  168. Bone Marrow Is a Preferential Homing Site for Autoreactive T-Cells in Type 1 Diabetes.
  169. Vessel wall stiffness in Type 1 diabetes, and the central hemodynamic effects of acute hypoglycemia.
  170. Plasma endothelin response to acute hypoglycaemia in adults with Type 1 diabetes.
  171. Overexpression of the autoantigen IA-2 puts beta cells into a pre-apoptotic state: autoantigen-induced, but non-autoimmune-mediated, tissue destruction.

    19 August 2007

  172. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.
  173. Length of gestation and gender are associated with HLA genotypes at risk for Type 1 diabetes (Italian DIABFIN 3).
  174. Epidemiology and genetic risk of type 1 diabetes among children in Aragon community, Spain.
  175. Short- and long-term glycaemic control and the state of the renin system in type 1 diabetes mellitus.

    12 August 2007

  176. Evidence of Increased Inflammation and Monocytic Activity in Patients with Type 1 Diabetes: plausible role in Microvascular Complications.
  177. Human chorionic gonadotropin is an immune modulator and can prevent autoimmune diabetes in NOD mice.
  178. Adiponectin levels do not predict clinical onset of type 1 diabetes in antibody-positive relatives.
  179. Evidence for a Role of Superoxide Generation in Glucose Induced ß-cell Dysfunction In Vivo.
  180. Non-invasive Magnetic Resonance Imaging of Microvascular Changes in Type 1 Diabetes.
  181. Polymorphism of bovine beta-casein and its potential effect on human health is the full text in PDF of an article referenced last week and explores the hypothesis that certain cows' milk may be contributing to the increase in type 1 diabetes and other illnesses.

    5 August 2007

  182. Modification of adverse inflammation is required to cure new-onset type 1 diabetic hosts.
  183. Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 mAb by enhancing recovery of {beta} cells.
  184. Impact of Oxidative Stress on the Endothelial Dysfunction of Children and Adolescents With Type 1 Diabetes Mellitus: Protection by Superoxide Dismutase?
  185. Rotavirus infections and development of type 1 diabetes: an evasive conundrum.
  186. IGF-1 and leptin associate with fetal HDL-cholesterol at birth: examination in offspring of mothers with type 1 diabetes.
  187. Influence of glycemic variables on hemoglobin A1c.
  188. Polymorphism of bovine beta-casein and its potential effect on human health.
  189. Immunoregulatory dendritic cells to prevent and reverse new-onset Type 1 diabetes mellitus.

    29 July 2007

  190. Oxidative stress in childhood type 1 diabetes: Results from a study covering the first 20 years of evolution.
  191. Prevalence and prognostic implications of the metabolic syndrome in community-based patients with type 1 diabetes: The Fremantle Diabetes Study.
  192. Presence of GAD Antibodies During Gestational Diabetes Mellitus Predicts Type 1 Diabetes.
  193. The Effect of Medical Therapy and Islet Cell Transplantation on Diabetic Nephropathy: An Interim Report.
  194. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey.

    22 July 2007

  195. A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. See also Uncovered: New Gene Linked To Type 1 Diabetes In Children, USA and Gene Discovered For Type 1 Diabetes In Children.
  196. Carotid intima-media thickness in pediatric type 1 diabetes patients.
  197. Peripheral artery tonometry demonstrates altered endothelial function in children with type 1 diabetes.
  198. Renal hemodynamic changes and renal functional reserve in children with type I diabetes mellitus.
  199. The age at diagnosis of type 1 diabetes continues to decrease in Belgian boys but not in girls: a 15-year survey.
  200. Advanced Glycation End Products (AGEs) and Cardiovascular Disease (CVD) in Diabetes.
  201. The hemoglobin glycation index is not an independent predictor of the risk of microvascular complications in the Diabetes Control and Complications Trial.
  202. Estimated prevalence of peripheral neuropathy and associated pain in adults with diabetes in France.
  203. Continuous stimulation of human glucagon-like peptide-1 (7-36) amide in a mouse model (NOD) delays onset of autoimmune type 1 diabetes.
  204. Simvastatin protects against multiple low dose streptozotocin induced type 1 diabetes in CD-1 mice and recurrence of disease in non obese diabetic mice. Free full text available in PDF format.
  205. The vicious cycle of apoptotic beta-cell death in type 1 diabetes.

    15 July 2007

  206. Diabetic nephropathy in 27,805 children, adolescents and adults with type 1 diabetes: effect of diabetes duration, HbA1c, hypertension, dyslipidemia, diabetes onset and gender.
  207. Early changes in glomerular size selectivity in young adults with type 1 diabetes and retinopathy. Results from the Diabetes Incidence Study in Sweden.
  208. Association of VEGF-1499C-->T polymorphism with diabetic nephropathy in type 1 diabetes mellitus.
  209. Higher Prevalence of Elevated Albumin Excretion in Youth with Type 2 than Type 1 Diabetes: The SEARCH for Diabetes in Youth Study.
  210. The effect of exercise on the absorption of inhaled human insulin via the AERx® iDMS in people with type 1 diabetes.

    8 July 2007

  211. Generation of Insulin-producing Cells From Human Bone Marrow Mesenchymal Stem Cells By Genetic Manipulation.
  212. Maternal Psychological Reaction to Newborn Genetic Screening for Type 1 Diabetes.
  213. Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes. See also CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans.
  214. Australian children and adolescents with type 1 diabetes have low vitamin D levels. Also available in PDF format (see page 3).
  215. T cell immunomodulation-the Holy Grail of therapeutic tolerance.
  216. Prevalence of autoimmune diseases in islet transplant candidates with severe hypoglycaemia and glycaemic lability: previously undiagnosed coeliac and autoimmune thyroid disease is identified by screening.
  217. Glucagon, in Concert with Insulin, Supports the Postabsorptive Plasma Glucose Concentration in Humans.
  218. Gluten-free but also gluten-enriched (gluten+) diet prevent diabetes in NOD mice; the gluten enigma in type 1 diabetes.
  219. Lower heart rate variability is associated with higher plasma concentrations of IL-6 in type 1 diabetes.

    1 July 2007

  220. Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy.
  221. Telmisartan Shows an Equivalent Effect of Vitamin C in Further Improving Endothelial Dysfunction After Glycemia Normalization in Type 1 Diabetes.
  222. Effect of oral insulin on insulin autoantibody levels in the Diabetes Prevention Trial Type 1 oral insulin study.
  223. The effect of ramipril therapy on cytokines and parameters of incipient diabetic nephropathy in patients with type 1 diabetes mellitus.
  224. Prospective Study of Type 1 and Type 2 Diabetes and Risk of Stroke Subtypes; The Nurses' Health Study.
  225. Loss of Angiotensin-Converting Enzyme-2 (Ace2) Accelerates Diabetic Kidney Injury.

    24 June 2007

  226. Exenatide blocks JAK1-STAT1 in pancreatic beta cells.
  227. Bone metabolism is linked to disease duration and metabolic control in type 1 diabetes mellitus.
  228. Rapid-onset type 1 diabetes associated with cytomegalovirus infection and islet autoantibody synthesis. Free full text available in PDF format.
  229. Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development.
  230. Organ specific autoantibodies in preclinical and early clinical type 1 diabetes in Turkey.
  231. Influence of stressful life events on the onset of Type 1 diabetes in childhood.

    17 June 2007

  232. Pancreatic islet transplantation, what has been achieved since Edmonton break-through.
  233. Participant and Parent Experiences in the Parenteral Insulin Arm of the Diabetes Prevention Trial for Type 1 Diabetes.
  234. Islet autoantibody development during follow-up of high-risk children from the general Norwegian population from three months of age: Design and early results from the MIDIA study.
  235. Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes.
  236. Interferons induce an antiviral state in human pancreatic islet cells.
  237. Differentiation of transplanted microencapsulated fetal pancreatic cells.
  238. Diabetes Patient Successfully Transplanted in World-first DiabeCell® Trial. See also LCT awarded world-first IANZ accreditation for xenotransplantation laboratory and Pig cells transplanted into patient.
  239. Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance. See also European researchers poke away at Type 1 diabetes with effective vaccination in mice.
  240. Improved Monitoring of the Hyperglycemic State in Type 1 Diabetes Patients by Use of the Glycoalbumin/HbA1c Ratio.

    10 June 2007

  241. Stressful life events and psychological dysfunctions before the onset of type 1 diabetes mellitus.
  242. Cognitive performance in type 1 diabetes patients is associated with cerebral white matter volume.
  243. Decreased blood dendritic cell counts in type 1 diabetic children.
  244. Simple switch turns cells embryonic; Technique removes need for eggs or embryos.
  245. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Free full text available in HTML and PDF formats.

    3 June 2007

  246. Major increase in Type 1 diabetes-no support for the Accelerator Hypothesis.
  247. Engineered enteroendocrine cells secrete insulin in response to glucose and reverse hyperglycemia in diabetic mice.
  248. Association between Glycosylated Hemoglobin Level and Cardiovascular and All-Cause Mortality in Type 1 Diabetes.
  249. Oxidant stress, immune dysregulation, and vascular function in type I diabetes.
  250. Meta-analysis of the effects of n-3 polyunsaturated fatty acids on lipoproteins and other emerging lipid cardiovascular risk markers in patients with type 2 diabetes.
  251. A method to predict the metabolic effects of changes in insulin treatment in subgroups of a large population based patient cohort.
  252. The Role of Insulin Resistance in Predicting the Progression to Type 1 Diabetes.
  253. Thiazolidinediones and Heart Failure: A Teleo-Analysis.
  254. Length of gestation and gender are associated with HLA genotypes at risk for Type 1 diabetes (Italian DIABFIN 3).

    27 May 2007

  255. Normalization of the IGF-IGFBP Axis by Sustained Nightly Insulinization in Type 1 Diabetes.
  256. Orange Juice or Fructose Intake Does Not Induce Oxidative and Inflammatory Response.
  257. Oxidant stress, immune dysregulation, and vascular function in type I diabetes.
  258. Presence of GAD-antibodies during gestational diabetes predicts type 1 diabetes.
  259. Effect of BMI on Lifetime Risk for Diabetes in the U.S.
  260. Childhood Obesity and Metabolic Imprinting: The Ongoing Effects of Maternal Hyperglycemia.
  261. Identification of insulin autoantibodies of IgA isotype that preferentially target non-human insulin.
  262. Genetic and phenotypic diversity of echovirus 30 strains and pathogenesis of type 1 diabetes.
  263. Discordant expression of pro-B-type and pro-C-type natriuretic peptide in newborn infants of mothers with type 1 diabetes.
  264. Downregulation of GLP-1 and GIP Receptor Expression by Hyperglycemia; Possible Contribution to Impaired Incretin Effects in Diabetes.

    20 May 2007

  265. Control of T cell mediated autoimmunity by metabolite flux to N-glycan biosynthesis. Free full text available in PDF format. See also Glucosamine-like supplement inhibits multiple sclerosis, type 1 diabetes.
  266. The Role of HLA Class I Gene Variation in Autoimmune Diabetes. Free full text available in HTML and PDF formats.
  267. Human pancreatic islet endothelial cells express coxsackievirus and adenovirus receptor and are activated by coxsackie B virus infection.
  268. Transfusion of Apoptotic ß Cells Induces Immune Tolerance to ß Cell Antigens and Prevents Type 1 Diabetes in NOD Mice.
  269. Multiple variants in Vascular Endothelial Growth Factor (VEGF) are risk factors for time to severe retinopathy in type 1 diabetes: The DCCT/EDIC genetics study.
  270. HLA-DPB1*0402 Protects Against Type 1A Diabetic Autoimmunity in the Highest Risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY Population.
  271. Biomarkers of susceptibility to type 1 diabetes with special reference to the Indian population. Free full text available in PDF format.
  272. Does autonomic diabetic neuropathy influence microcirculation reactivity in adolescents with diabetes type 1?
  273. Interleukin 12 as an anti-angiogenic mediator in type 1 diabetic children.
  274. Otoneurologic findings in Type 1 Diabetes mellitus patients. Free full text available in HTML and PDF formats.
  275. Insulin resistance and metabolic syndrome in children of parents with diabetes mellitus.

    13 May 2007

  276. A high incidence of type 1 diabetes and an alarming increase in the incidence of type 2 diabetes among young adults in Finland between 1992 and 1996.
  277. Three-yr follow-up of a type 1 diabetes mellitus patient with an islet xenotransplant.
  278. Long-term treatment with the apolipoprotein mimetic peptide D-4F increases antioxidants and vascular repair in Type I diabetic rats. Free full text available in PDF format.

    6 May 2007

  279. Insulin dependant diabetes mellitus: implications for male reproductive function. See also Diabetes may cut male fertility and Diabetes Damages DNA In Men's Sperm And May Affect Fertility, According To Study.
  280. Intracoronary ultrasound examinations reveal significantly more advanced coronary atherosclerosis in people with type 1 diabetes than in age- and sex-matched non-diabetic controls.
  281. A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulin-resistant diabetic rats.
  282. Two-week treatment with pravastatin improves ventriculo-vascular haemodynamic interactions in young men with type 1 diabetes.
  283. Conversion of embryonic stem cells into pancreatic beta-cell surrogates guided by ontogeny.
  284. Sleep deprivation reduces the lymphocyte count in a non-obese mouse model of type 1 diabetes mellitus. Free full text available in HTML and PDF formats.

    29 April 2007

  285. Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody.
  286. Rising Incidence of Type 2 Diabetes in Children in the U.K.
  287. Marked increase in type 1 diabetes mellitus incidence in children aged 0-14 yr in Victoria, Australia, from 1999 to 2002.
  288. Perinatal risk factors for childhood Type 1 diabetes in Western Australia—a population-based study (1980–2002).
  289. Steep increase of incidence of childhood diabetes since 1999 in Austria. Time trend analysis 1979-2005. A nationwide study.
  290. Incidence of type 1 diabetes mellitus in the 0- to 17-yr-old Israel population, 1997-2003.
  291. Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission.
  292. GAD65 autoantibody epitopes in adult patients with latent autoimmune diabetes following GAD65 vaccination.
  293. Telmisartan shows an equivalent effect of vitamin C in further improving endothelial dysfunction after glycemia normalization in type 1 diabetes.
  294. Combination therapy with an ACE inhibitor and an angiotensin receptor blocker for diabetic nephropathy: a meta-analysis.
  295. A method for assessing quality of control from glucose profiles.
  296. Type 1 diabetes-related epidemiological, clinical and laboratory findings. An evaluation with special regard to autoimmunity in children.
  297. Benefits of Information Technology–Enabled Diabetes Management.
  298. Maternal history of type 2 diabetes is associated with diabetic nephropathy in type 1 diabetic patients.
  299. Clustering of Risk Factors in Parents of Patients With Type 1 Diabetes and Nephropathy.
  300. Contrast sensitivity and fluorescein angiography in evaluating the ocular changes in the relation to the diabetes mellitus type I compensation in young adult patients.
  301. Diabetic ketoacidosis in Denmark Incidence and mortality estimated from public health registries.
  302. Changing perspectives in diabetes: their impact on its classification.
  303. Hematopoietic Stem Cells Derived from Adult Donors are Not a Source of Pancreatic Beta Cells in Adult Non Diabetic Humans.
  304. Selective unresponsiveness to beta cell autoantigens after induction immunosuppression in pancreas transplantation with anti-interleukin-2 receptor antibody versus anti-thymocyte globulin.
  305. Chromium Treatment Has No Effect in Patients With Type 2 Diabetes in a Western Population.

    22 April 2007

  306. Mutations in KATP Channel Genes cause Transient Neonatal Diabetes and Permanent Diabetes in Childhood or Adulthood.
  307. Early infancy onset of type 1A diabetes mellitus in dizygotic twins: association with genetic and environmental factors. Free Portuguese language full text available in HTML and PDF formats.
  308. Brief Hyperglycaemia In The Early Pregnant Rat Increases Fetal Weight At Term By Stimulating Placental Growth And Affecting Placental Nutrient Transport.

    15 April 2007

  309. Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus. Free full text available in HTML and PDF formats. See also Type I diabetics live without insulin in stem cell experiment and Stem cells re-set the immune systems of diabetes patients.
  310. Association between glycosylated hemoglobin level and 16-year incidence of chronic kidney disease in type 1 diabetes.
  311. Changes in Depressive Symptoms and Glycemic Control in Diabetes Mellitus.
  312. Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset.
  313. Relationship between interstitial and blood glucose in type 1 diabetes patients: delay and the push-pull phenomenon revisited.

    8 April 2007

  314. Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase. Free full text available in PDF format. See also Hypoglycemia, functional brain failure, and brain death and Glucose Triggers Brain Cell Death In Rats After Hypoglycemic Coma.
  315. Moving towards efficient therapies in type 1 diabetes: To combine or not to combine?
  316. Shorter remission period in young versus older children with diabetes mellitus type 1.
  317. No evidence for increased self-reported cognitive failure in Type 1 and Type 2 diabetes: a cross-sectional study.
  318. Lack of evidence of hypervolemia in children with insulin-dependent diabetes mellitus.
  319. Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis.
  320. Perinatal factors associated with subsequent diabetes mellitus in the child: record linkage study.
  321. Relationship between increased relative birthweight and infections during pregnancy in children with a high-risk diabetes HLA genotype.
  322. Relationship between gestational diabetes mellitus and type 2 diabetes: evidence of mitochondrial dysfunction.
  323. Generation of functional islet-like clusters after monolayer culture and intracapsular aggregation of adult human pancreatic islet tissue.

    1 April 2007

  324. Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. See also LCT Reports Major Step Forward for Islet Transplantation in Diabetes Patient, DiabeCell - Living Cell Technologies, and 10 years on, pig cells still fighting diabetes.
  325. Evaluation of promoters for driving efficient transgene expression in neonatal porcine islets.
  326. Glucose responsive insulin production from human embryonic germ (EG) cell derivatives.
  327. Islet cell transplantation today.
  328. Prediction and Prevention of Type 1 Diabetes: Progress, Problems, and Prospects.
  329. Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission.
  330. Spatiotemporal Trends and Age-Period-Cohort Modeling of the Incidence of Type 1 Diabetes Among Children Aged <15 Years in Norway 1973–1982 and 1989–2003.
  331. Effect Of Body Mass Index On Lifetime Risk For Diabetes Mellitus In The United States.
  332. Intramuscular injection of islet neogenesis-associated protein peptide stimulates pancreatic islet neogenesis in healthy dogs.
  333. GAD65 autoantibody epitopes in adult patients with latent autoimmune diabetes following GAD65 vaccination.
  334. Insulin-Expressing Colonies Developed From Murine Embryonic Stem Cell–Derived Progenitors.
  335. Ischemic Vascular Damage Can Be Repaired by Healthy, but Not Diabetic, Endothelial Progenitor Cells.
  336. Pharmacological treatment of diabetic retinopathy.
  337. Genome-Wide Linkage Analyses to Identify Loci for Diabetic Retinopathy.
  338. Acute Hyperglycemia Induces a Global Downregulation of Gene Expression in Adipose Tissue and Skeletal Muscle of Healthy Subjects.
  339. Subclinical right ventricular dysfunction in diabetes mellitus-an ultrasonic strain/strain rate study.

    25 March 2007

  340. Glycaemic control, health status and treatment satisfaction with continuous intraperitoneal insulin infusion.
  341. Normalization of the IGF-IGFBP-axis by Sustained Nightly Insulinization in Type 1 Diabetes.
  342. Are Insights Gained From NOD Mice Sufficient To Guide Clinical Translation? Another Inconvenient Truth.
  343. Childhood obesity as a risk factor for diabetes mellitus type I: the accelerator hypothesis.
  344. Dendritic cells with TGFß-1 differentiate naïve CD4+CD25– T cells into islet-protective Foxp3+ regulatory T cells. See also Successful Islet Cell Transplant Without Immunosuppressive Therapy In Mice With Type 1 Diabetes.
  345. Autoimmunity and beta cell regeneration in mouse and human Type 1 diabetes: The peace is not enough.
  346. Coxsackievirus infections and NOD mice: Relevant models of protection from, and induction of, type 1 diabetes.
  347. Immunoisolating Pancreatic Islets by Encapsulation with Selective Withdrawal.
  348. Mouse models for cardiovascular complications of type 1 diabetes.
  349. Possibility of insulin-producing cells derived from mouse embryonic stem cells for diabetes treatment. Free full text available in PDF format.

    18 March 2007

  350. Major childhood infectious diseases and other determinants associated with type 1 diabetes: a case-control study.
  351. Coxsackie B4 virus infection of {beta} cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.
  352. Chemokines as drug targets in type 1 diabetes.
  353. Translational Mini-Review Series on Type 1 Diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.
  354. Translational Mini-Review Series on Type 1 Diabetes: Immune-based therapeutic approaches for type 1 diabetes.
  355. Building a bridge between clinical and basic research: the phenotypic elements of familial predisposition to type 1 diabetes.
  356. MICA marks additional risk factors for Type 1 diabetes on extended HLA haplotypes: An association and meta-analysis.
  357. Simultaneous onset of type 1 diabetes in monozygotic twins younger than 1 year.
  358. Erythrocyte susceptibility to oxidative stress and antioxidant status in patients with type 1 diabetes.
  359. Defining the roles of T cell membrane proteinase and CD44 in type 1 diabetes.
  360. Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice.

    11 March 2007

  361. Adaptive Closed-Loop Control Provides Blood-Glucose Regulation Using Dual Subcutaneous Insulin and Glucagon Infusion in Diabetic Swine.
  362. Microalbuminuria and the Risk for Early Progressive Renal Function Decline in Type 1 Diabetes.
  363. Vitamin D supplementation and diabetes-related autoimmunity in the ABIS study.
  364. Prevalence of atopy in children with type 1 diabetes mellitus in central Taiwan.
  365. HLA-DRB1*08 allele may help to distinguish between type 1 diabetes mellitus and type 2 diabetes mellitus in Mexican children.
  366. Selected immunologic and biochemical risk factors of the retinopathy and nephropathy development in children with diabetes mellitus type 1.
  367. Renal and retinal microangiopathy after 15 years of follow-up study in a sample of Type 1 diabetes mellitus patients.
  368. Prevalence and risk factors for diabetic retinopathy--a study of 217 patients from University of Malaya Medical Centre.
  369. Antibodies to GAD65 and peripheral nerve function in the DCCT.
  370. Clustering of Risk Factors in Parents of Patients with Type 1 Diabetes and Nephropathy.
  371. Are glomerular volume differences between type 1 and type 2 diabetic patients pathologically significant?
  372. Genetic study reveals how endocrine cell types are produced in the pancreas.
  373. Autoimmunity and clinical course in children with type 1, type 2, and type 1.5 diabetes.
  374. Type 1 Diabetes Genetic Risk Much Higher Than Previous Estimates.

    4 March 2007

  375. Increasing Incidence of Type 1 Diabetes in 0- to 17-Year-Old Colorado Youth. See also CU documents diabetes rise in kids.
  376. GAD Autoantibody Affinity and Epitope Specificity Identify Distinct Immunization Profiles in Children at Risk for Type 1 Diabetes.
  377. Simultaneous Control of Hyperglycemia and Oxidative Stress Normalizes Endothelial Function in Type 1 Diabetes.
  378. Glycemic and Risk Factor Control in Type 1 Diabetes - Results from 13,612 patients in a national diabetes register.
  379. NOS3 Polymorphisms Are Associated With Arterial Stiffness in Children With Type 1 Diabetes.
  380. Patients With Chronic Pancreatitis Have Islet Progenitor Cells in Their Ducts, but Reversal of Overt Diabetes in NOD Mice by Anti-CD3 Shows No Evidence for Islet Regeneration.
  381. CCL4 Protects From Type 1 Diabetes by Altering Islet ß-Cell–Targeted Inflammatory Responses.
  382. Limited Capacity of Human Adult Islets Expanded In Vitro to Redifferentiate Into Insulin-Producing ß-Cells.
  383. Insulin Resistance, the Metabolic Syndrome, and Complication Risk in Type 1 Diabetes - "Double diabetes" in the Diabetes Control and Complications Trial.
  384. Association of Television Viewing With Fasting and 2-h Postchallenge Plasma Glucose Levels in Adults Without Diagnosed Diabetes.
  385. Association Between Serum Concentrations of Persistent Organic Pollutants and Insulin Resistance Among Nondiabetic Adults.
  386. An Accurate Risk Score Based on Anthropometric, Dietary, and Lifestyle Factors to Predict the Development of Type 2 Diabetes.

    25 February 2007

  387. Paternal smoking is associated with a decreased prevalence of type 1 diabetes mellitus among offspring in two national British birth cohort studies (NCDS and BCS70).
  388. Uncomplicated Type 1 Diabetes Is Associated With Increased Asymmetric Dimethylarginine Concentrations. Free full text available in PDF format.
  389. Fetal growth is increased by maternal type 1 diabetes and HLA DR4-related gene interactions.
  390. Secular trends, disease maps and ecological analyses of the incidence of childhood onset Type 1 diabetes in Northern Ireland, 1989-2003.
  391. Human parechovirus 1 infections in young children-no association with type 1 diabetes.
  392. High T-helper-1 cytokines but low T-helper-3 cytokines, inflammatory cytokines and chemokines in children with high risk of developing type 1 diabetes.

    18 February 2007

  393. The Prediction of Major Outcomes of Type 1 Diabetes: A 12 year prospective evaluation of three separate definitions of the Metabolic Syndrome, and their components and estimated glucose disposal rate: The Pittsburgh Epidemiology of Diabetes Complications Study Experience.
  394. Caspase Inhibitor Therapy Enhances Marginal Mass Islet Graft Survival and Preserves Long Term Function in Islet Transplantation.
  395. Transient chorea in a patient with type 1 diabetes may induce a reduction in insulin demand through increased spontaneous movements.
  396. Engineered Enteroendocrine Cells Secrete Insulin in Response to Glucose and Reverse Hyperglycemia in Diabetic Mice.
  397. Cell therapy for diabetes mellitus.

    11 February 2007

  398. Questioning Four Preconceived Ideas on Immunotherapy of Clinical Type 1 Diabetes: Lessons from Recent CD3 Antibody Trials. Free full text also available in PDF format.
  399. Association of Postprandial Hyperglycemia with in Vitro LDL Oxidation in Non-Smoking Patients with Type 1 Diabetes - a Cross-Sectional Study. Free full text available in HTML and PDF formats.
  400. Immunotherapy After Recent-Onset Type 1 Diabetes: Combinatorial Treatment for Achieving Long-Term Remission in Humans? Free full text available in PDF format.
  401. Polyclonal Anti-T-Cell Therapy for Type 1 Diabetes Mellitus of Recent Onset. Free full text available in HTML and PDF formats.
  402. Modulating the Autoimmune Response in Type 1 Diabetes: A Report on the 64th Scientific Sessions of the ADA, June 2004, Orlando, FL, USA. Free full text available in PDF format.
  403. Mucosal tolerance to prevent type 1 diabetes: can the outcome be improved in humans? Free full text available in HTML and PDF formats.
  404. Genes Mediating Environment Interactions in Type 1 Diabetes. Free full text available in HTML and PDF formats.
  405. B cells in autoimmune diabetes. Free full text available in PDF format.
  406. Interfering with vagal nerve activity in mice prevents diabetes and hypertension.
  407. Suppression of Hyperglycemia in NOD Mice After Inoculation With Recombinant Vaccinia Viruses.
  408. Imbalance in Th Cell Polarization and its Relevance in Type 1 Diabetes Mellitus. Free full text available in HTML and PDF formats.
  409. Elimination of insulitis and augmentation of islet {beta} cell regeneration via induction of chimerism in overtly diabetic NOD mice. Free full text available in PDF format.
  410. Longitudinal changes in epitope recognition of autoantibodies against glutamate decarboxylase 65 (GAD65Ab) in prediabetic adults developing diabetes.
  411. Regulation of the inducible nitric oxide synthase and sodium pump in type 1 diabetes.
  412. Prevalence and incidence rate of diabetes mellitus in a Swedish community during 30 years of follow-up.
  413. Higher incidence of type 1 diabetes in males--a study in teenagers and young adults in Krakow region in 1987-1999.
  414. Temporal trends in mortality of patients with diabetes mellitus suffering acute myocardial infarction: a comparison of over 3000 patients between 1995 and 2003.

    4 February 2007

  415. Stem cells with potential to generate insulin producing cells in man. Free full text available in PDF format.
  416. Tolerance Induction and Endogenous Regeneration of Pancreatic beta-Cells in Established Autoimmune Diabetes. Free full text available in HTML and PDF formats.
  417. Existence of Islet Regenerating Factors within the Pancreas. Free full text available in HTML and PDF formats.
  418. Replenishing Peripheral CD4+ Regulatory T Cells: A Possible Immune-Intervention Strategy in Type 1 Diabetes? Free full text available in HTML and PDF formats.
  419. The Application of Umbilical Cord Blood Cells in the Treatment of Diabetes Mellitus. Free full text available in HTML and PDF formats.
  420. Questioning Four Preconceived Ideas on Immunotherapy of Clinical Type 1 Diabetes: Lessons from Recent CD3 Antibody Trials. Free full text available in PDF format.
  421. Approaches Towards Endogenous Pancreatic Regeneration.
  422. Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes. Free full text available in PDF format.
  423. Insulin gene VNTR, CTLA-4 +49A/G and HLA-DQB1 alleles distinguish latent autoimmune diabetes in adults from type 1 diabetes and from type 2 diabetes group.
  424. Serum and urinary cytokine homeostasis and renal tubular function in children with type 1 diabetes mellitus.
  425. Continuous intraperitoneal insulin infusion does not increase the risk of organ-specific autoimmune disease in type 1 diabetic patients: results of a multicentric, comparative study.
  426. Glucose and insulin metabolism in obese youth.
  427. Rising incidence of type 2 diabetes in children in the United Kingdom. Free full text available in PDF format.

    28 January 2007

  428. Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet beta cell microchimerism. See also Cells passed from mother to child may be first step in developing new treatments for Type 1 diabetes and similar diseases, Diabetes repair 'occurs in womb', Well-meaning mums, and Mom's Stem Cells Might Treat Child's Diabetes.
  429. Can we identify adolescents at high risk for nephropathy before the development of microalbuminuria?
  430. New therapies aimed at the preservation or restoration of beta cell function in type 1 diabetes.
  431. Glycodelin: a novel serum anti-inflammatory marker in type 1 diabetic retinopathy during pregnancy.
  432. Growth in the first year of life and the risk of type 1 diabetes in a Danish population.
  433. Prevalence of autoimmune diseases in islet transplant candidates with severe hypoglycaemia and glycaemic lability: previously undiagnosed coeliac and autoimmune thyroid disease is identified by screening.
  434. Increased forearm blood flow in longstanding Type 1 diabetic patients without microvascular complications. Free full text available in HTML and PDF formats.
  435. Endothelial function in patients with type 1 diabetes evaluated by skin capillary recruitment.
  436. Androgens and Diabetes in Men.
  437. Antiviral treatment of Coxsackie B virus infection in human pancreatic islets.
  438. Proinsulin: a unique autoantigen triggering autoimmune diabetes. Free full text available in HTML and PDF formats.

    21 January 2007

  439. Effect of exenatide on Beta cell function after islet transplantation in type 1 diabetes.
  440. Growth hormone-IGF-I axis and growth velocity in Chinese children with type 1 diabetes mellitus.
  441. An IGF-I gene polymorphism modifies the risk of developing persistent microalbuminuria in type 1 diabetes.
  442. Association between Haptoglobin Gene Variants and Diabetic Nephropathy: Haptoglobin Polymorphism in Nephropathy Susceptibility.
  443. Systemic autoantibodies and their correction in patients with diabetic retinopathy in type 1 diabetes mellitus.
  444. Magnetic resonance imaging: a reliable method for measuring pancreatic volume in Type 1 diabetes.
  445. Model based study on monitoring ketone bodies to improve safety in intensive insulin therapy.
  446. Fulminant type 1 diabetes as a high risk group for diabetic microangiopathy-a nationwide 5-year-study in Japan.
  447. Plasmid-based gene therapy of diabetes mellitus.
  448. Effect of complete Freund's adjuvant on islet beta cell apoptosis and its mechanism in non-obese diabetic mice.
  449. Obesity and Diabetes in the Developing World — A Growing Challenge. Free full text available in PDF format.
  450. Metabolic syndrome : Origin within the central nervous system?

    14 January 2007

  451. Changes in Renal Function after Clinical Islet Transplantation: Four-Year Observational Study.
  452. Living donor islet transplantation, the alternative approach to overcome the obstacles limiting transplant.
  453. Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft.
  454. Comparison of conventional and non-invasive techniques for the early identification of diabetic neuropathy in children and adolescents with type 1 diabetes.
  455. Serum protease inhibitor concentrations and total antitrypsin activity in diabetic and non-diabetic children during adolescence.
  456. At-Risk and Recent-Onset Type 1 Diabetic Subjects Have Increased Apoptosis in the CD4+CD25+ T-Cell Fraction. Free full text available in HTML and PDF formats (click on the link from the HTML page for PDF).
  457. Serum IL-1beta, IL-2, and IL-6 in insulin-dependent diabetic children. Free full text available in HTML and PDF formats.
  458. Pancreatic alpha-cell differentiation by mesenchyme-to-epithelial transition: implications for cell-based therapies in children.
  459. Peptide-pulsed immature dendritic cells reduce response to beta cell target antigens and protect NOD recipients from type I diabetes.
  460. Acute liver dysfunction complicated with uncontrollable glycemia due to insulin antibody: successful treatment with glucocorticoid and lispro insulin. Free full text available in PDF format.

    7 January 2007

  461. Left ventricular function in normotensive young adults with well-controlled type 1 diabetes mellitus.
  462. Prevalence of Autoantibody-Negative Diabetes Is Not Rare at All Ages and Increases with Older Age and Obesity.
  463. Environmental factors in the development of Type 1 diabetes.
  464. Involvement of Oxidative Stress in the Pathogenesis of Diabetes.
  465. The role of gut hormones in glucose homeostasis.
  466. Immunomodulation techniques in a pig-to-rat model of xenoislet transplantation to prolong graft survival.

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